马良飞 1尹翎 1方婷 1曾西西 1佟佳璇 1马献昆1
作者信息
- 1. 610000 成都,中国五冶集团有限公司医院康复医学科
- 折叠
摘要
Abstract
Objective To observe the effect of repetitive transcranial magnetic stimulation(rTMS)combined with virtual reality(VR)technology on cognitive impairment after stroke.Methods One hundred and fifty-three PSCI patients admitted to the Rehabilitation Medicine Department of China MCC5 Group Corp.Ltd.Hospital from April 2021 to August 2022 were selected as the research subjects.They were divided into a combination group,rTMS group,and control group using a random number table method.According to the inclusion and exclusion criteria,49 cases were obtained in the combination group,48 cases in the rTMS group,and 48 cases in the control group.The control group received routine cognitive rehabilitation training and false magnetic stimulation,the rTMS group switched to real rTMS stimulation on top of the control group,while the combination group added VR technology on top of the rTMS group.All three groups were intervened for 8 weeks.Before and after 8 weeks of treatment,the Montreal cognitive assessment scale(MoCA),Stroop color word test(SCWT),and National Institutes of Health stroke scale(NIHSS)were observed in three groups of patients,and the levels of hypersensitive C-reactive protein(hs-CRP),brain derived neurotrophic factor(BDNF),serum neuron specific enolase(NSE),homocysteine(HCY),and superoxide dismutase(SOD)were measured.Results The MoCA score and SCWT results of the combination group were higher than those of the rTMS group and the control group,while the NIHSS score was lower than that of the control group,and the difference was statistically significant(P＜0.05).The BDNF level in the combination group was higher than that in the rTMS group and control group,while the NSE and HCY levels were lower than those in the rTMS group and control group,the hs-CRP level was lower than that in the control group,and the SOD level was higher than that in the control group,with statistical significance(P＜0.05).Conclusion rTMS combined with VR technology can improve cognitive impairment,promote neural function recovery,and improve related biochemical indicators in PSCI patients.关键词
脑卒中后认知障碍/重复经颅磁刺激/虚拟现实技术Key words
Post-stroke cognitive impairment/Repetitive transcranial magnetic stimulation/Virtual reality technology
