中外医学研究2024，Vol.22Issue(4)：153-156,4.DOI:10.14033/j.cnki.cfmr.2024.04.038
二甲双胍联合SGLT2抑制剂治疗PCOS合并T2DM患者的研究进展
Research Progress of the Combination of Metformin and SGLT2 Inhibitors in the Treatment of PCOS Complicated with T2DM
摘要
Abstract
Polycystic ovary syndrome(PCOS)patients are often complicated by type 2 diabetes mellitus(T2DM),and the two are related and influence each other in etiology and pathogenesis.Metformin is the basic drug for T2DM and is also clinically used for PCOS.However,the therapeutic effect of Metformin alone is limited,and the combination with other drugs has become an important treatment choice.Sodium-glucose cotransporter 2(SGLT2)inhibitors,as a class of drugs with a unique mechanism of action,have a good therapeutic effect and a broad application range.Now,considering metformin combined with SGLT2 inhibitors in the treatment of PCOS combined with T2DM patients,this article reviews the research progress and mechanism of metformin combined with SGLT2 inhibitors in the treatment of PCOS combined with T2DM patients.关键词
多囊卵巢综合征/2型糖尿病/二甲双胍/钠-葡萄糖协同转运蛋白2抑制剂Key words
PCOS/T2DM/Metformin/SGLT2 inhibitors引用本文复制引用
左金雨,郑燕..二甲双胍联合SGLT2抑制剂治疗PCOS合并T2DM患者的研究进展[J].中外医学研究,2024,22(4):153-156,4.基金项目
垫江县科技项目(djkjxm2021shmskjcxyw001) （djkjxm2021shmskjcxyw001）
