中药材2023，Vol.46Issue(7)：1693-1696,4.DOI:10.13863/j.issn1001-4454.2023.07.018
藏药臭蚤草化学成分研究
Chemical Constituents of Tibetan Medicine Pulicaria insignis
摘要
Abstract
Objective:To study the chemical constituents of Pulicaria insignis.Methods:The compounds from the petroleum ether fraction of 65% ethanol extract of Pulicaria insignis inflorescence were isolated and purified by silica gel,Sephadex LH-20 and D101 macroporous resin.The structures were identified by physicochemical properties and spectral analysis.Results:Thirteen compounds were isolated from Pulicaria insignis inflorescence and identified as 8β-methoxyeremophil-7(11)-ene-12,8α(14β,6α)-olide(1),8β-hydroxyeremophil-7(11)-ene-12,8α(4β,6α)-diolide(2),furanoeremophilan-4β,6α-olide(3),8β-eremophil-7(11)-ene-12,8α(4β,6α)-diolide(4),6β-hydroxyerelimphran-7(11)-en-12,8β-olid(5),8β,10β-dihydroxyeremophilenolide(6),(6α,8α)-6-hydroxyeremo-phil-7(11)-en-12,8-olide(7),10β-hydroxyeremophilenolide(8),1(10)-en-2-oxo-7α-isopropanoleremophilane(9),(4S,5S,7R)-11-hydroxyeremophil-1(10)-ene-2,9-dione(10),8β-hydroxyeremophil-7(11)-en-12,8-olide(11),4-methoxybenzonic acid(12),luteolin(13),respectively.Conclusion:Among them,compounds 1 to 11 are isolated from Pulicaria genus for the first time.关键词
藏药/臭蚤草/化学成分Key words
Tibetan medicine/Pulicaria insignis Drumm ex Dunn/Chemical constituents分类
医药卫生引用本文复制引用
刘方圆,曾金祥,孙杰,王钰洁,钟渊涵,杨静,李敏..藏药臭蚤草化学成分研究[J].中药材,2023,46(7):1693-1696,4.基金项目
国家重点研发计划项目(2019YFC1712300) （2019YFC1712300）
