组织工程与重建外科杂志2024，Vol.20Issue(1)：129-134,156,7.DOI:10.3969/j.issn.1673-0364.2024.01.015
合成生物学驱动再生医学创新:从细胞工程到器官修复
Synthetic biology is driving regenerative medicine innovation:From cell engineering to organ repair
摘要
Abstract
With the rapid development of synthetic biology,its combination with regenerative medicine has opened up new pathways for cell engineering and organ repair.Synthetic biology techniques can be used to precisely repair genetic defects,reprogram mature cells into induced pluripotent stem cells,and perform targeted differentiation for regenerative medical treatment of patients'own cells.In addition,synthetic biology can also be applied to design tissue engineering materials and 3D printing artificial organs.Despite the challenges such as biosafety and ethics,the progress in synthetic biology will drive the development of regenerative medicine towards precision and personalized treatment.The convergence of synthetic biology and regenerative medicine will facilitate further improvements and innovations in various core technologies for the advancement of regenerative medicine.关键词
合成生物学/再生医学/细胞工程/器官修复/个体化精准治疗Key words
Synthetic biology/Regenerative medicine/Cell engineering/Organ repair/Individualized precision therapy分类
医药卫生引用本文复制引用
田宝星,侯梦洁,王斌..合成生物学驱动再生医学创新:从细胞工程到器官修复[J].组织工程与重建外科杂志,2024,20(1):129-134,156,7.基金项目
国家重点研发计划(2022YFC2703700,2022YFC2703704) （2022YFC2703700,2022YFC2703704）
上海交通大学医学院附属第九人民医院先天性肢体畸形生物样本库建设项目(YBKB202108)、罕见病注册登记项目(JYHJB202205). （YBKB202108）
