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广金钱草中非黄酮类化学成分的研究

吴云秋 闫炳雄 黄媛 阮丽君 姚彩云 刘茹欣 宋志军

中药材2023,Vol.46Issue(6):1429-1433,5.
中药材2023,Vol.46Issue(6):1429-1433,5.DOI:10.13863/j.issn1001-4454.2023.06.018

广金钱草中非黄酮类化学成分的研究

Study on Non-flavonoids of Desmodium styracifolium

吴云秋 1闫炳雄 1黄媛 1阮丽君 2姚彩云 1刘茹欣 3宋志军1

作者信息

  • 1. 广西壮族自治区药用植物园西南濒危药材资源开发国家工程实验室,广西 南宁 530023
  • 2. 广西壮族自治区药用植物园广西药用资源保护与遗传改良重点实验室,广西南宁 530023
  • 3. 广西医科大学药学院,广西南宁 530021
  • 折叠

摘要

Abstract

Objective:To study the chemical constituents of Desmodium styracifolium.Methods:The ethanol extract of Desmodium styracifolium were isolated and purified by silica gel column chromatography,Sephadex LH-20 gel column chromatography,ODS column chromatography,preparation HPLC.The structures were identified by spectral data and physicochemical properties.Results:Twenty non-flavonoids compounds were isolated from Desmodium styracifolium and identified as(+)-dehydrovomifoliol(1),(-)-loliolide(2),β-si-tosterol(3),salicylic acid(4),(+)-isololiolide(5),6,7-dimethoxy-4-hydroxy-1-naphthoic acid(6),2,5-dimethoxy-1,4-benzenedicar-boxylic acid(7),p-hydroxyacetophenone(8),3-formylindole(9),vanillic acid(10),isovanillic acid(11),p-hydroxybenzoic acid(12),4,5-dihydroblumenol(13),β-dauosterol(14),7-oxo-stigmasta-5,25-diene-3-O-β-D-glucopyranoside(15),desmodilactone(16),12-hydroxyjasmonic acid(17),maltol(18),4,5-dimethyl-3-hydroxy-2,5-dihydrofuran-2-one(19),desmodimine(20),respectively.Conclu-sion:Among them,compunds 1,2,5 to 9,13,15,17,19 are isolated from Desmodium styracifolium for the first time.

关键词

广金钱草/化学成分/分离鉴定/广金钱草碱

Key words

Desmodium styracifolium(Osb.)Merr./Chemical constituents/Isolation and identification/Desmodimine

分类

医药卫生

引用本文复制引用

吴云秋,闫炳雄,黄媛,阮丽君,姚彩云,刘茹欣,宋志军..广金钱草中非黄酮类化学成分的研究[J].中药材,2023,46(6):1429-1433,5.

基金项目

中国科学院科技服务网络计划(STS计划)区域重点项目A类(KFJ-STS-QYZD-2021-03-004) (STS计划)

广西壮族自治区中医药管理局横向委托项目(GXZYYZZ-202201) (GXZYYZZ-202201)

中药材

OA北大核心CSTPCD

1001-4454

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