Light(Science & Applications)2024，Vol.13Issue(1)：P.80-90,11.DOI:10.1038/s41377-023-01352-7
Observation of a single protein by ultrafast X-ray diffraction
Tomas Ekeberg 1Dameli Assalauova 2Johan Bielecki 3Rebecca Boll 3Benedikt J.Daurer 4Lutz A.Eichacker 5Linda E.Franken 6Davide E.Galli 7Luca Gelisio 2Lars Gumprecht 8Laura H.Gunn 9Janos Hajdu 1Robert Hartmann 10Dirk Hasse 1Alexandr Ignatenko 2Jayanath Koliyadu 11Olena Kulyk 12Ruslan Kurta 3Markus Kuster 3Wolfgang Lugmayr 13Jannik Lübke 14Adrian P.Mancuso 15Tommaso Mazza 3Carl Nettelblad 16Yevheniy Ovcharenko 3Daniel E.Rivas 3Max Rose 2Amit K.Samanta 8Philipp Schmidt 3Egor Sobolev 17Nicusor Timneanu 18Sergey Usenko 3Daniel Westphal 1Tamme Wollweber 19Lena Worbs 20Paul Lourdu Xavier 21Hazem Yousef 3Kartik Ayyer 22Henry N.Chapman 14Jonas A.Sellberg 23Carolin Seuring 24Ivan A.Vartanyants 2Jochen Küpper 14Michael Meyer 3Filipe R.N.C.Maia25
作者信息
- 1. Laboratory of Molecular Biophysics,Department of Cell and Molecular Biology,Uppsala University,Husargatan 3(Box 596),SE-75124 Uppsala,Sweden
- 2. Deutsches Electronen-Synchrotron DESY,Notkestrasse 85,22607 Hamburg,Germany
- 3. European XFEL,Holzkoppel 4,22869 Schenefeld,Germany
- 4. Diamond Light Source,Harwell Science&Innovation Campus,Didcot OX110DE,UK
- 5. University of Stavanger,Centre Organelle Research,Richard-Johnsensgate 4,4021 Stavanger,Norway
- 6. Leibniz Institute for Experimental Virology(HPI),Centre for Structural Systems Biology,Notkestraße 85,22607 Hamburg,Germany
- 7. Dipartimento di Fisica“Aldo Pontremoli”,Universitàdegli Studi di Milano,via Celoria 16,20133 Milano,Italy
- 8. Center for Free-Electron Laser Science,DESY,22607 Hamburg,Germany
- 9. Laboratory of Molecular Biophysics,Department of Cell and Molecular Biology,Uppsala University,Husargatan 3(Box 596),SE-75124 Uppsala,Sweden Plant Biology Section,School of Integrative Plant Science,Cornell University,Ithaca,NY 14853,USA
- 10. PNSensor GmbH,Otto-Hahn-Ring 6,D-81739 München,Germany
- 11. European XFEL,Holzkoppel 4,22869 Schenefeld,Germany Biomedical and X-Ray Physics,Department of Applied Physics,AlbaNova University Center,KTH Royal Institute of Technology,SE-10691 Stockholm,Sweden
- 12. ELI Beamlines/IoP Institute of Physics AS CR,v.v.i.,Na Slovance 2,18221 Prague 8,Czech Republic
- 13. Multi-User CryoEM Facility,Centre for Structural Systems Biology,Notkestr.85,22607 Hamburg,Germany University Medical Center Hamburg-Eppendorf(UKE),Martinistrasse 52,20246 Hamburg,Germany
- 14. Center for Free-Electron Laser Science,DESY,22607 Hamburg,Germany The Hamburg Center for Ultrafast Imaging,Universität Hamburg,Luruper Chaussee 149,22761 Hamburg,Germany Department of Physics,Universität Hamburg,Luruper Chaussee 149,22761 Hamburg,Germany
- 15. European XFEL,Holzkoppel 4,22869 Schenefeld,Germany Department of Chemistry and Physics,La Trobe Institute for Molecular Science,La Trobe University,Melbourne,VIC 3086,Australia
- 16. Division of Scientific Computing,Science for Life Laboratory,Department of Information Technology,Uppsala University,Box 337SE-75105 Uppsala,Sweden
- 17. European XFEL,Holzkoppel 4,22869 Schenefeld,Germany European Molecular Biology Laboratory,c/o DESY,Notkestrasse 85,22607 Hamburg,Germany
- 18. Department of Physics and Astronomy,Uppsala University,Box 516SE-75120 Uppsala,Sweden
- 19. The Hamburg Center for Ultrafast Imaging,Universität Hamburg,Luruper Chaussee 149,22761 Hamburg,Germany Department of Physics,Universität Hamburg,Luruper Chaussee 149,22761 Hamburg,Germany Max Planck Institute for the Structure and Dynamics of Matter,Luruper Chaussee 149,22761 Hamburg,Germany Center for Free-Electron Laser Science,Luruper Chaussee 149,22761 Hamburg,Germany
- 20. Center for Free-Electron Laser Science,DESY,22607 Hamburg,Germany Department of Physics,Universität Hamburg,Luruper Chaussee 149,22761 Hamburg,Germany
- 21. European XFEL,Holzkoppel 4,22869 Schenefeld,Germany Center for Free-Electron Laser Science,DESY,22607 Hamburg,Germany Max Planck Institute for the Structure and Dynamics of Matter,Luruper Chaussee 149,22761 Hamburg,Germany
- 22. The Hamburg Center for Ultrafast Imaging,Universität Hamburg,Luruper Chaussee 149,22761 Hamburg,Germany Max Planck Institute for the Structure and Dynamics of Matter,Luruper Chaussee 149,22761 Hamburg,Germany Center for Free-Electron Laser Science,Luruper Chaussee 149,22761 Hamburg,Germany
- 23. Biomedical and X-Ray Physics,Department of Applied Physics,AlbaNova University Center,KTH Royal Institute of Technology,SE-10691 Stockholm,Sweden
- 24. Multi-User CryoEM Facility,Centre for Structural Systems Biology,Notkestr.85,22607 Hamburg,Germany Department of Chemistry,Universität Hamburg,20146 Hamburg,Germany
- 25. Laboratory of Molecular Biophysics,Department of Cell and Molecular Biology,Uppsala University,Husargatan 3(Box 596),SE-75124 Uppsala,Sweden NERSC,Lawrence Berkeley National Laboratory,Berkeley,CA 94720,USA
- 折叠
摘要
关键词
smallest/intense/ultrafast分类
数理科学引用本文复制引用
Tomas Ekeberg,Dameli Assalauova,Johan Bielecki,Rebecca Boll,Benedikt J.Daurer,Lutz A.Eichacker,Linda E.Franken,Davide E.Galli,Luca Gelisio,Lars Gumprecht,Laura H.Gunn,Janos Hajdu,Robert Hartmann,Dirk Hasse,Alexandr Ignatenko,Jayanath Koliyadu,Olena Kulyk,Ruslan Kurta,Markus Kuster,Wolfgang Lugmayr,Jannik Lübke,Adrian P.Mancuso,Tommaso Mazza,Carl Nettelblad,Yevheniy Ovcharenko,Daniel E.Rivas,Max Rose,Amit K.Samanta,Philipp Schmidt,Egor Sobolev,Nicusor Timneanu,Sergey Usenko,Daniel Westphal,Tamme Wollweber,Lena Worbs,Paul Lourdu Xavier,Hazem Yousef,Kartik Ayyer,Henry N.Chapman,Jonas A.Sellberg,Carolin Seuring,Ivan A.Vartanyants,Jochen Küpper,Michael Meyer,Filipe R.N.C.Maia..Observation of a single protein by ultrafast X-ray diffraction[J].Light(Science & Applications),2024,13(1):P.80-90,11.基金项目
supported by the Universität Hamburg and DFG grant numbers(INST 152/772-1152/774-1152/775-1152/776-1152/777-1 FUGG) （INST 152/772-1152/774-1152/775-1152/776-1152/777-1 FUGG）
We acknowledge the support of funding from:Cluster of Excellence‘CUI:Advanced Imaging of Matter’of the Deutsche Forschungsgemeinschaft(DFG)-EXC 2056-project ID 390715994 （DFG）
ERC-2013-CoG COMOTION 614507 （）
NFR 240770 （）
Fellowship from the Joachim Herz Stiftung(P.L.X.) （P.L.X.）
P.L.X.and H.N.C.acknowledge support from the Human Frontiers Science Program(RGP0010/2017) （RGP0010/2017）
J.H.acknowledges support from the European Development Fund:Structural dynamics of biomolecular systems(ELIBIO)(CZ.02.1.01/0.0/0.0/15_003/0000447)EMBO long-term fellowship(ALTF 356-2018)awarded to L.E.F. （ELIBIO）
the Röntgen-Ångström Cluster(2015-06107 and 2019-06092) （2015-06107 and 2019-06092）
the Swedish Research Council(2017-05336,2018-00234 and 2019-03935) （2017-05336,2018-00234 and 2019-03935）
the Swedish Foundation for Strategic Research(ITM17-0455). （ITM17-0455）
