皮肤性病诊疗学杂志2024，Vol.31Issue(2)：118-122,5.DOI:10.3969/j.issn.1674-8468.2024.02.009
自噬与恶性黑色素瘤侵袭转移相关性研究进展
Research progress on the association of autophagy with invasion and metastasis of malig-nant melanoma
摘要
Abstract
Autophagy is a unique biological phenomenon of eukaryotic cells.Autophagy plays a very important role in promoting the survival of cells and actively adapting to different environ-ments.Autophagy plays a double-edged role in the development of tumor and metastasis.The re-search results on the link between autophagy and melanoma are inconsistent,likely due to the in-trinsic heterogeneity of melanoma and the difference in methodology of detecting autophagy.How-ever,the results of studies on different aspects support a link between autophagy and malignant melanoma,especially the important role of autophagy in targeted drug therapy.This paper reviews the dual role of autophagy in the biological processes of melanoma invasion and metastasis,in or-der to provide clues for the development of new therapeutic regimens and biomarkers for malignant melanoma.关键词
自噬/肿瘤/黑色素瘤Key words
autophagy/tumor/melanoma引用本文复制引用
高翔,赵雪宁,韩昭..自噬与恶性黑色素瘤侵袭转移相关性研究进展[J].皮肤性病诊疗学杂志,2024,31(2):118-122,5.基金项目
河北省卫生健康委科研基金项目(20220664) （20220664）
