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甲泼尼龙琥珀酸钠联合孟鲁司特钠治疗小儿过敏性紫癜的效果及对症状消失时间和炎症因子的影响

卢绪香

妇儿健康导刊2024,Vol.3Issue(4):116-119,4.
妇儿健康导刊2024,Vol.3Issue(4):116-119,4.

甲泼尼龙琥珀酸钠联合孟鲁司特钠治疗小儿过敏性紫癜的效果及对症状消失时间和炎症因子的影响

Effect of Methylprednisolone Sodium Succinate combined with Montelukast Sodium in the treatment of children with allergic purpura and its influence on symptom disappearance time and inflammatory factors

卢绪香1

作者信息

  • 1. 山东省莒县人民医院皮肤科,山东日照 276500
  • 折叠

摘要

Abstract

Objective To explore the effect of Methylprednisolone Sodium Succinate combined with Montelukast Sodium in the treatment of children with allergic purpura and its influence on symptom disappearance time and inflammatory factors.Methods A total of 76 children with allergic purpura admitted to Juxian People's Hospital from January 2020 to February 2023 were selected as the study objects.All the children were divided into the control group and the study group by the random number table method,with 38 cases in each group.The control group was treated with Methylprednisolone Sodium Succinate,and the observation group was treated with Montelukast Sodium on the basis of the control group.The levels of inflammatory factors,symptom disappearance time and treatment safety were compared between the two groups.Results The levels of C-reactive protein,interleukin-6 and tumor necrosis factor-α in the study group were lower than those in the control group(P<0.05).The disappearance time of various symptoms in the study group was shorter than that in the control group(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P<0.05).Conclusion Methylprednisolone Sodium Succinate combined with Montelukast Sodium in the treatment of children with allergic purpura can reduce inflammatory reaction and relieve clinical symptoms,which is worthy of clinical application.

关键词

甲泼尼龙琥珀酸钠/孟鲁司特钠/小儿过敏性紫癜/症状消失时间/炎症因子

Key words

Methylprednisolone Sodium Succinate/Montelukast Sodium/Children with allergic purpura/Symptom disappearance time/Inflammatory factor

分类

医药卫生

引用本文复制引用

卢绪香..甲泼尼龙琥珀酸钠联合孟鲁司特钠治疗小儿过敏性紫癜的效果及对症状消失时间和炎症因子的影响[J].妇儿健康导刊,2024,3(4):116-119,4.

妇儿健康导刊

2097-115X

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