妇儿健康导刊2024，Vol.3Issue(4)：190-194,5.
216例重症肺炎患儿肺泡灌洗液病原微生物分布特点分析
Analysis of pathogenic microorganism distribution characteristics in bronchoalveolar lavage fluid of 216 children with severe pneumonia
摘要
Abstract
Objective To analyze the pathogenic microorganism distribution characteristics in bronchoalveolar lavage fluid of 216 children with severe pneumonia.Methods A total of 216 children with severe pneumonia admitted to the Department of Pediatrics of Nanning Maternity and Child Health Hospital from June 2021 to June 2022 were selected,and bronchoalveolar lavage fluid was collected for multiple nucleic acid detection to analyze the pathogenic microorganism distribution characteristics.Results Among 216 children,210 were positive for pathogenic microorganisms,with a positive rate of 97.22%.The majority of the children were mixed infections,and most of them were mixed infections of bacteria and viruses.A total of 458 pathogenic microorganisms were detected.Bacteria accounted for 40.61%,among which Gram positive bacteria accounted for 49.46%,mainly Streptococcus pneumoniae.The proportion of Gram negative bacteria was 50.54%,mainly Haemophilus influenzae.Viruses accounted for 44.76%,mainly respiratory syncytial virus and cytomegalovirus.Fungi accounted for 8.73%,mainly Pneumocystis jirovecii.Mycoplasma pneumoniae accounted for 4.59%and Chlamydia pneumoniae accounted for 1.31%.Bacterial infection mainly occurred in early school age children,and fungal infection mainly occurred in infants.Bacterial infection was more common in spring,and viral infection was more common in autumn.Conclusion The positive rate of pathogen detection in bronchoalveolar lavage fluid of children with severe pneumonia is higher.The main bacterial infection is Streptococcus pneumoniae,and the main viral infection is respiratory syncytial virus,mostly mixed infection.There are age and season differences in the distribution of pathogenic microorganisms.关键词
重症肺炎/肺泡灌洗液/病原微生物/分布特点Key words
Severe pneumonia/Bronchoalveolar lavage fluid/Pathogenic microorganism/Distribution characteristic分类
医药卫生引用本文复制引用
唐盐林,黄树稳,颜云盈..216例重症肺炎患儿肺泡灌洗液病原微生物分布特点分析[J].妇儿健康导刊,2024,3(4):190-194,5.基金项目
广西壮族自治区卫生健康委员会自筹经费科研课题(Z20211403). （Z20211403）
