武警医学2024，Vol.35Issue(3)：222-225,229,5.
苯磺酸瑞马唑仑联合舒芬太尼对宫腔镜手术患者血流动力学及应激反应的影响
Effects of remazolam besylate combined with sufentanil on hemodynamics and stress re-sponse in patients undergoing hysteroscopy surgery
杨彦军 1焦岩 2段峰 1路一平 1郇颖静 1杨润楠3
作者信息
- 1. 450052 郑州,武警河南总队医院 门诊部
- 2. 450052 郑州,武警河南总队医院 麻醉科
- 3. 450052 郑州,武警河南总队医院 医学工程科
- 折叠
摘要
Abstract
Objective To evaluate the effects of remazolam besylate anesthesia on hemodynamics and stress response in pa-tients undergoing hysteroscopic surgery.Methods A total of 94 female patients undergoing hysteroscopic surgery were selected and di-vided into study group and control group by random number table method(n=47).The control group was given propofol combined with sufentanil,and the study group was given remazolam besylate combined with sufentanil.The hemodynamics,stress response indexes,pain and sedation,and the occurrence of adverse reactions were compared between the two groups.Results Heart rate(HR)and mean arterial pressure(MAP)of the two groups significantly decreased when the laryngeal mask was inserted(T1),cervical dilation(T2)and laryngeal mask was removed(T3)compared with that before anesthesia induction(T0)(P＜0.05),and the blood oxygen saturation(SpO2)of the control group significantly decreased at T1 and T0(P＜0.05).HR and MAP of T1,T2 and T3 in the study group were significantly higher than those in the control group(P＜0.05).Epinephrine(E),norepinephrine(NE)and cortisol(Cor)in both groups were significantly higher than those before surgery at 2 h,12 h and 48 h after surgery(P＜0.05),and E,NE and Cor in the study group were significantly lower than those in the control group(P＜0.05).The resting VAS score of the study group was significantly lower than that of the control group at 2 h and 12 h after surgery(P＜0.05),and the Ramsay score was significantly higher than that of the control group(P＜0.05).The incidence of postoperative adverse reactions in the study group(6.38%)was signifi-cantly lower than that in the control group(29.79%,P＜0.05).Conclusions Compared with propofol combined with sufentanil,rem-azolam besylate combined with sufentanil has more stable hemodynamics,lower postoperative stress reaction and pain,good sedation effect and less adverse reactions in hysteroscopic surgery.关键词
苯磺酸瑞马唑仑/丙泊酚/舒芬太尼/宫腔镜手术/血流动力学/应激反应Key words
remazolam besylate/propofol/sufentanil/hysteroscopy/hemodynamics/stress response分类
临床医学引用本文复制引用
杨彦军,焦岩,段峰,路一平,郇颖静,杨润楠..苯磺酸瑞马唑仑联合舒芬太尼对宫腔镜手术患者血流动力学及应激反应的影响[J].武警医学,2024,35(3):222-225,229,5.
