中国组织工程研究2024，Vol.28Issue(29)：4652-4656,5.DOI:10.12307/2024.533
骨水泥-椎体体积比与骨质疏松椎体压缩骨折治疗效果的关系
Relationship between bone cement-vertebral volume ratio and therapeutic effect of osteoporotic vertebral compression fractures
摘要
Abstract
BACKGROUND:Percutaneous vertebroplasty has become the main treatment method for osteoporotic vertebral compression fractures due to its advantages of convenient operation and low trauma.However,the optimal bone cement-vertebral volume ratio has not been determined. OBJECTIVE:To investigate the effect of bone cement-vertebral volume ratio on percutaneous vertebroplasty for osteoporotic vertebral compression fractures. METHODS:The clinical data of 100 patients with single-stage osteoporotic vertebral compression fractures admitted to Xinjiang Bazhou People's Hospital from July 2019 to July 2022 were retrospectively analyzed.All patients received percutaneous vertebroplasty.According to the bone cement-vertebral volume ratio,they were divided into the low volume group(15%≤ratio≤20%)and the high volume group(20%<ratio≤25%)with 50 cases in each group.The visual analog scale score,Oswestry disability index,vertebral anterior margin height,Cobb angle of injured vertebra,bone cement distribution pattern,and bone cement leakage rate were analyzed before surgery,3 days and 1 year after surgery. RESULTS AND CONCLUSION:(1)Compared with the preoperative results,the visual analog scale scores,vertebral anterior margin height,Cobb angle of injured vertebra at 3 days and 1 year after surgery,and Oswestry disability index at 1 year after surgery were significantly improved in 100 patients(P<0.05).There were no significant differences in visual analog scale scores at 3 days and 1 year after surgery and Oswestry disability index at 1 year after surgery between the low volume group and the high volume group(P>0.05).The vertebral anterior margin height in the low volume group was lower than that in the high volume group at 3 days and 1 year after surgery(P<0.05).The Cobb angle of the injured vertebrae in the low volume group was higher than that in the high volume group at 3 days and 1 year after surgery(P<0.05).(2)There were 10 H-type and 40 O-type bone cement distributions in the low volume group.There were 36 H-type and 14 O-type bone cement distributions in the high volume group,and there was no significant difference in bone cement distributions between the two groups(P<0.05).The bone cement leakage rate in the high volume group and low volume group was 10%and 6%,respectively.(3)It is indicated that both low and high bone cement-vertebral volume ratios can improve postoperative pain and functional dysfunction,but high bone cement-vertebral volume ratio can improve the morphological recovery of injured vertebral,which may be related to the fact that the distribution of bone cement in this group is more H-type.关键词
骨水泥-椎体体积比/经皮椎体成形术/骨质疏松性椎体压缩骨折/骨水泥分布形态/疼痛/功能障碍Key words
bone cement-vertebral volume ratio/percutaneous vertebroplasty/osteoporotic vertebral compression fracture/bone cement distribution pattern/pain/dysfunction分类
医药卫生引用本文复制引用
马超,丁江平,王斌,牛奔,穆合塔尔·吾买尔,唐国柱,杨红涛,冯新文..骨水泥-椎体体积比与骨质疏松椎体压缩骨折治疗效果的关系[J].中国组织工程研究,2024,28(29):4652-4656,5.基金项目
新疆维吾尔自治区自然科学基金项目(2022D01A03),项目负责人:丁江平 （2022D01A03）
新疆巴音郭楞蒙古自治州科学技术研究项目(202312),项目负责人:冯新文 （202312）
新疆巴州人民医院青年科研基金专项项目(BY202308),项目负责人:马超 Natural Science Foundation of Xinjiang Uygur Autonomous Region,No.2022D01A03(to DJP) （BY202308）
Science and Technology Research Project of Bayingol Mongolian Autonomous Prefecture,No.202312(to FXW) （to FXW）
Special Project of Youth Scientific Research Fund of Xinjiang Bazhou People's Hospital,No.BY202308(to MC) （to MC）
