临床医学工程2024，Vol.31Issue(3)：279-280,2.DOI:10.3969/j.issn.1674-4659.2024.03.0279
免疫球蛋白和超敏C反应蛋白在小儿手足口病临床检验中的价值探讨
Discussion on the Value of Immunoglobulin and Hypersensitive C-reactive Protein in Clinical Detection of Children with Hand-Foot-Mouth Disease
刘秀秀 1林前雄2
作者信息
- 1. 福建省福州儿童医院检验科,福建福州 350005
- 2. 福建省立医院金山院区检验输血科,福建福州 350028
- 折叠
摘要
Abstract
Objective To explore the value of immunoglobulin and hypersensitive C-reactive protein(hs-CRP)in clinical detection of children with hand-foot-mouth disease.Methods 73 children with hand-foot-mouth disease were selected as the observation group,while 73 healthy children with physical examination during the same period were selected as the control group.The immunoglobulin and hs-CRP levels of both groups were detected.ROC curve was drawn to evaluate the value of single and combined detection in the diagnosis of hand-foot-mouth disease.Results The IgG and IgA of the observation group were lower than those of the control group,while the IgM and hs-CRP were higher than those of the control group(P＜0.05).The AUC of the combined detection in the diagnosis of hand-foot-mouth disease in children was 0.914,higher than that of single detection(P＜0.05).The sensitivity,specificity,and accuracy of the combined detection in the diagnosis of hand-foot-mouth disease in children are higher than those of single detection(P＜0.05).Conclusions Children with hand-foot-mouth disease have immune barrier damage and inflammatory reactions,and abnormal changes in immunoglobulin and hs-CRP may occur.The combined detection of above indicators in clinic can improve the diagnostic accuracy of children with hand-foot-mouth disease and facilitate guidance for subsequent treatment.关键词
免疫球蛋白/超敏C反应蛋白/小儿手足口病/诊断价值Key words
Immunoglobulin/Hypersensitive C-reactive protein/Children with hand-foot-mouth disease/Diagnostic value分类
医药卫生引用本文复制引用
刘秀秀,林前雄..免疫球蛋白和超敏C反应蛋白在小儿手足口病临床检验中的价值探讨[J].临床医学工程,2024,31(3):279-280,2.
