临床医学工程2024，Vol.31Issue(3)：337-338,2.DOI:10.3969/j.issn.1674-4659.2024.03.0337
酶联免疫法和金标法对HIV抗体的检测结果比较
Comparison of Detection Results of Enzyme-Linked Immunosorbent Assay and Gold Labeling Method for HIV Antibodies
季晓丽 1卢莹莹 2赵小瑞1
作者信息
- 1. 南阳市卧龙区疾病预防控制中心卫生检验检测中心,河南南阳 473000
- 2. 南阳市卧龙区妇幼保健院检验科,河南南阳 473000
- 折叠
摘要
Abstract
Objective To explore the detection results of HIV antibody by enzyme-linked immunosorbent assay(ELISA)and gold labeling method,and to identify more effective clinical screening methods for AIDS.Methods 264 suspected AIDS patients were selected and taken blood after admission to detect HIV antibody by ELISA and gold labeling method.The consistency between ELISA and gold labeling method with clinical examination results based on clinical diagnosis results were compared.The diagnostic efficacy of ELISA and gold labeling method for AIDS were compared.Results 225 of 264 suspected AIDS patients were definitely diagnosed by clinical screening test and confirmatory test.κ test analysis showed that ELISA results had high consistency with clinical diagnosis(κ=0.897,P＜0.05);Gold labeling method results had high consistency with the clinical diagnosis(κ=0.902,P＜0.05).No statistical difference was found in the sensitivity,specificity and accuracy between ELISA and gold labeling method in the diagnosis of AIDS(P＞0.05).Conclusions ELISA and gold labeling method have better detection effect on HIV antibody,which can provide more accurate data reference for clinical diagnosis of AIDS.In clinical detection,corresponding detection methods can be selected according to the patients'own conditions,and joint detection can be carried out when necessary.关键词
酶联免疫法/金标法/艾滋病/HIV抗体Key words
Enzyme linked immunosorbent assay/Gold labeling method/AIDS/HIV antibody分类
医药卫生引用本文复制引用
季晓丽,卢莹莹,赵小瑞..酶联免疫法和金标法对HIV抗体的检测结果比较[J].临床医学工程,2024,31(3):337-338,2.
