中医序贯疗法联合异维A酸治疗中重度痤疮的疗效观察OACSTPCD

Objective To observe the clinical efficacy of Chinese medicine sequential therapy(traditional Chinese medicine + fire acupuncture)combined with oral isotretinoin capsules in the treatment of moderate and severe acne.Methods Seventy-eight patients with moderate and severe acne in the author's hospital from September 2022 to November 2022 were selected and randomly divided into three groups of 26 cases each,with the treatment group given(Xiao Cuo Decoction + isotretinoin capsule + fire needle)at different stages,control group 1 given(Xiao Cuo Decoction + isotretinoin capsule)and control group 2 given(Xiao Cuo Decoction + fire needle),with fire needle therapy in the treatment group given after taking isotretinoin capsule for 2 The treatment group was treated with fire acupuncture after taking isotretinoin capsule for 2 weeks,once every 2 weeks.All three groups were treated continuously for 3 months.The clinical efficacy of each group was compared,and the time to regression of lesions,GAGS score,Skindex-16 score,adverse reactions and recurrence rate were compared.Results At the end of treatment,the total effective rate was 96.15%in the treatment group and 69.23%and 65.38%in the control group,respectively,the efficacy of the treatment group was higher than that of the control group(P＜0.05).The time to regression of skin lesions and GAGS scores of the treatment group were lower than those of the control group(P＜0.05),and the Skindex-16 scores of the treatment group were higher than those of the control group(P＜0.05).There was no significant difference in adverse effects among the groups(P＞0.05),and the recurrence rate 3.85%in the treatment group was lower than 30.76%and 34.61%in the control group(P＜0.05).Conclusion Chinese medicine squential therapy for moderate and severe acne can significantly improve the efficacy,promote the regression of lesions,and improve the quality of life of patients,and is worthy of clinical application.