中国美容医学2024，Vol.33Issue(3)：100-103,4.
女性型脱发患者的血清维生素D水平及与雄激素的相关性研究
Serum Vitamin D Level in Female Pattern Hair Loss Patients and Relationship with Androgen
摘要
Abstract
Objective To explore the relationship between serum vitamin D levels and androgen levels in female pattern hair loss(FPHL),and to provide new clues for the pathogenesis and treatment of FPHL.Methods We analyzed serum vitamin D levels in 70 patients with female pattern alopecia and 65 healthy subjects recruited from hospital and physical examination center.We also analyzed the relationship between serum vitamin D levels and disease severity,demographic characteristics,lifestyle habits,and androgens.Results The mean levels of serum vitamin D significantly decreased in FPHL,compared to those healthy controls[(13.59±5.82)ng/ml vs(15.94±6.89)ng/ml].There was a positive correlation between vitamin D and sex hormone binding globulin(SHBG)(P＜0.05),and a negative correlation between vitamin D and free testosterone(P＜0.05).Serum vitamin D levels was significantly lower in those patients with decrease SHBG or elevated free testosterone.However,no correlation was found between vitamin D level and severity,demographic characteristics,and lifestyle in FPHL.Conclusion The vitamin D level of FPHL is significantly lower than that of healthy people,suggesting that the decrease of vitamin D may be one of the pathogenesis factors of FPHL.The correlation between SHBG,free testosterone and vitamin D may be the reason of the vitamin D deficiency in FPHL,which needs more studies to verify.Serum vitamin D,SHBG and free testosterone should be monitored more actively in FPHL patients.关键词
女性型脱发/维生素D/雄激素/性激素结合球蛋白/游离睾酮Key words
female pattern hair loss/vitamin D/androgen/sex hormone binding globulin/free testosterone分类
医药卫生引用本文复制引用
陈宇凌,白杨娟,王奕欣,董薪,李利..女性型脱发患者的血清维生素D水平及与雄激素的相关性研究[J].中国美容医学,2024,33(3):100-103,4.基金项目
国家自然科学基金(编号:82173441) （编号:82173441）
