中国美容医学2024，Vol.33Issue(3)：120-123,4.
Q开关1 064 nm Nd∶YAG激光联合氨甲环酸超声导入治疗黄褐斑疗效观察
Observation on Therapeutic Effects of Q-switched 1 064 nm Nd︰YAG Laser Combined with Phonophoresis with Tranexamic Acid in the Treatment of Chloasma
喻路 1李欢1
作者信息
- 1. 重庆市大足区人民医院皮肤科 重庆 402360
- 折叠
摘要
Abstract
Objective This study aimed at investigate the cosmetic results of Q-switched 1 064 nm Nd:YAG laser combined with phonophoresis with tranexamic acid in the treatment of chloasma.Methods A total of 60 patients with chloasma who were treated in the People's Hospital of Dazu between April 2022 and August 2022 were selected as the research subjects.They were randomly divided into the Nd:YAG laser group,the tranexamic acid group and the combined treatment group with 20 patients in each group.Patients in the three groups were treated with Q-switched 1 064 nm Nd:YAG laser,phonophoresis with tranexamic acid,and Q-switched 1 064 nm Nd:YAG laser combined with phonophoresis with tranexamic acid,respectively.The three groups were compared in terms of clinical efficacy,adverse reactions and 6-month recurrence rate.Results The total treatment response rate in the combined treatment group were higher when compared with those in the Nd:YAG laser group and the tranexamic acid group(P＜0.05).The Melasma Area and Severity Index(MASI)score of the combined treatment group after 12 weeks of treatment was significantly lower when compared with the scores of the Nd:YAG laser group and the tranexamic acid group(P＜0.05).The total satisfaction rate in the combined treatment group was higher when compared with those in the Nd:YAG laser group and the tranexamic acid group(P＜0.05).The incidence rates of adverse reactions(15.00%,15.00%and 5.00%)in the three groups showed no statistically significant difference(P＞0.05).The recurrence rate in the combined treatment group was lower than that in the Nd:YAG laser group and tranexamic acid group(P＜0.05).Conclusion Q-switched 1 064 nm Nd:YAG laser combined with phonophoresis with tranexamic acid is superior to single therapy in the treatment of chloasma.In addition,it is safe and the recurrence rate is lower.关键词
黄褐斑/氨甲环酸/Q开关Nd∶YAG激光/超声导入Key words
chloasma/tranexamic acid/Q switch Nd∶YAG laser/phonophoresis分类
医药卫生引用本文复制引用
喻路,李欢..Q开关1 064 nm Nd∶YAG激光联合氨甲环酸超声导入治疗黄褐斑疗效观察[J].中国美容医学,2024,33(3):120-123,4.
