中国临床药理学杂志2024，Vol.40Issue(5)：768-772,5.DOI:10.13699/j.cnki.1001-6821.2024.05.029
特应性皮炎生物靶向治疗研究发展
Research progress of biological targeted therapy for atopic dermatitis
摘要
Abstract
Atopic dermatitis(AD)is the most common chronic inflammatory skin disease.For decades,the treatment of AD has been limited to local corticosteroid or calcineurin inhibitors,and light therapy or systemic immunosuppressive drug for moderate to severe AD patients.With the in-depth study of the pathogenesis of AD,many local and systemic targeted therapy drugs are being developed,which may change the treatment options of AD.This review combination with the latest clinical trials give a summarize on the type,mechanism,efficacy and safety of biological targeted therapy for AD,to provide a theoretical basis for the individualized treatment of AD.关键词
特应性皮炎/生物制剂/靶向治疗/临床试验Key words
atopic dermatitis/biological agents/targeted therapy/clinical trial分类
医药卫生引用本文复制引用
刘盈,姚采君,曾晖,陈季芳,周春..特应性皮炎生物靶向治疗研究发展[J].中国临床药理学杂志,2024,40(5):768-772,5.基金项目
广州市科技计划基础与应用基础基金资助项目(202201011806) （202201011806）
广东省教育厅科研基金资助项目(2017KTSCX213) （2017KTSCX213）
