中国普通外科杂志2024,Vol.33Issue(2):176-183,8.DOI:10.7659/j.issn.1005-6947.2024.02.003
重视代谢功能障碍相关性脂肪性肝病相关肝内胆管癌的研究
Paying attention to the research of intrahepatic cholangiocarcinoma linked to metabolic dysfunction-associated fatty liver disease
摘要
Abstract
Over the past 20 years,the global incidence of metabolic dysfunction-associated fatty liver disease(MAFLD)has increased dramatically,affecting more than 30%of the global population.Meanwhile,over the past 40 years,the global incidence of intrahepatic cholangiocarcinoma(ICC)has also grown by 140%.In addition,previous studies have indicated that various forms of liver inflammation are closely associated with the occurrence and development of ICC.This suggests that MAFLD may play an important role in the occurrence,development,and prognosis of ICC.This article aims to summarize the current research status of MAFLD-related ICC,review the shortcomings in existing studies,and outline future research directions to provide a foundation for further exploration and in-depth study in this field.关键词
胆管肿瘤/胆管,肝内/代谢障碍相关性脂肪性肝病Key words
Bile Duct Neoplasms/Bile Ducts,Intrahepatic/Metabolic Dysfunction-Associated Fatty Liver Disease分类
医药卫生引用本文复制引用
李宗龙,陈家璐,唐玥,覃德龙,汤朝晖,全志伟..重视代谢功能障碍相关性脂肪性肝病相关肝内胆管癌的研究[J].中国普通外科杂志,2024,33(2):176-183,8.基金项目
国家自然科学基金资助项目(81772521) (81772521)
上海交通大学医学院附属新华医院院级临床研究培育基金资助项目(17CSK06) (17CSK06)
上海交通大学医学院多中心临床研究基金资助项目(DLY201807). (DLY201807)