中国实用外科杂志2024，Vol.44Issue(2)：159-163,5.DOI:10.19538/j.cjps.issn1005-2208.2024.02.09
肠道菌群移植外科临床应用的争议与共识
Controversy and consensus on the clinical application of Fecal microbiota transplantation in surgery
摘要
Abstract
Fecal microbiota transplantation(FMT)refers to the transplantation of functional microbiota from healthy human feces into the patient's intestines in a certain way,to regulate the balance of gut microbiota,rebuilding gut microbiota,and achieve the goal of preventing and treating internal and external intestinal diseases.In recent years,FMT treatment has expanded from recurrent Clostridioides difficile infection(rCDI)to inflammatory bowel disease(IBD),irritable bowel syndrome(IBS),chronic constipation,and other diseases.The field of FMT treatment has also extended from internal medicine and pediatrics to surgery.Multiple clinical studies have shown that the application of FMT during the perioperative period can improve the cure rate of surgical patients,reduce postoperative complications,and improve postoperative nutritional status and quality of life.However,due to the short duration of FMT surgical research and the lack of high-quality clinical studies with large samples,the methodology of FMT itself is complex and there are methodological issues such as donor selection,standardized treatment of fecal samples,and establishment of FMT transplantation pathways that need to be improved.Further research and discussion are needed on the specific treatment plan and efficacy of FMT applied in the perioperative period of surgery.关键词
菌群移植/微生态/粪便Key words
fecal microbiota transplantation/microecology/feces分类
医药卫生引用本文复制引用
秦环龙,方芷殉,陈启仪,田宏亮..肠道菌群移植外科临床应用的争议与共识[J].中国实用外科杂志,2024,44(2):159-163,5.基金项目
国家自然科学基金项目(No.82100698) （No.82100698）
同济大学附属第十人民医院攀登人才计划项目(2021SYPDRC045) （2021SYPDRC045）
