中国实用外科杂志2024，Vol.44Issue(2)：194-198,5.DOI:10.19538/j.cjps.issn1005-2208.2024.02.16
肿瘤相关性肌肉减少症的发病危险因素分析
Analysis of risk factors for tumor-associated sarcopenia:a study based on the NHANES database
摘要
Abstract
Objective To explore the risk factors of tumor-associated sarcopenia by using the National Health And Nutrition Examination Survey(NHANES)database,Methods The data of 410 cancer patients in the NHANES database from 2011 to 2018 were analyzed.Appendicular skeleton muscle index(ASMI)was used of diagnose sarcopenia.Clinical features of these patients were analyzed for risk factors for sarcopenia.Results Uni-variate analysis revealed that high-tension physical activity of less than 10 minutes per week was a risk factor for sarcopenia in male cancer patients(P＜0.1).While,blood calcium,blood potassium,blood phosphate,and plasma albumin,be informed whether to be overweight or not,high-tension physical work less than 10 minutes per week,be willing to lose weight or not,attempted to lose weight in the past year or not,urine leakage in non-physical activities,high-density lipoprotein-cholesterol,total bilirubin,self-recognition of body weight were factors with statistical significance(All P＜0.1).Multi-variate analysis revealed that high-tension physical activity of less than 10 minutes per week was a risk factor for sarcopenia in male cancer patients,while,serum potassium,urine leakage in non-physical activities,high-density lipoprotein--cholesterol,recognized low weight were risk factors in female cancer patients(All P＜0.05).Conclusion The risk factors for tumor-associated sarcopenia were distinct because of gender.In male cancer patients,insufficient exercise was the main cause.In female cancer patients,serum biochemical nutrition-related indexes,urine leakage,and questionnaire self-cognition were the main reasons.It is essential to provide a reference for future screening and diagnosis of tumor-associated sarcopenia patients.关键词
肌肉减少症/肿瘤/危险因素Key words
sarcopenia/tumor/risk factors分类
临床医学引用本文复制引用
肖先皓,宋禾,周建平..肿瘤相关性肌肉减少症的发病危险因素分析[J].中国实用外科杂志,2024,44(2):194-198,5.基金项目
辽宁省自然科学基金项目(No.2023-MS-170) （No.2023-MS-170）
