中国畜牧杂志2024，Vol.60Issue(3)：73-78,6.DOI:10.19556/j.0258-7033.20230325-01
猪β-防御素129和114的表达及其功能研究进展
Research Progress on the Expression and Function of Porcine β-defensin 129 and β-defensin 114
摘要
Abstract
β-defensins are highly conserved small cationic peptide widely distributed in vertebrates,contributing to the antimicrobial action,innate and adaptive immunity.Porcine β-defensin 129(pBD129)and porcine β-defensin 114(pBD114)are widely distributed in various organs and tissues of pigs.In addition to resisting pathogenic microorganisms and regulating immune function,they also play an important role in reproductive development.pBD129 and pBD114 are highly expressed in the epididymis of boars.Recent works have confirmed that the involvement of these two defensins in the process of maturation,motility and fertilization of sperm.This paper reviews recent advances in pBD129 and pBD114,including the expression and distribution,signal pathways involved in,as well as related biological functions,in order to provide theoretical and reference basis for the functional study and application of pBD129 and pBD114.关键词
pBD129/pBD114/免疫/繁殖/猪Key words
pBD129/pBD114/Immunity/Reproduction/Pig分类
农业科技引用本文复制引用
李菊,黄晓刚,韩贝贝,刘松柏,高凤磊,李莉,赵云翔,张守全,卫恒习..猪β-防御素129和114的表达及其功能研究进展[J].中国畜牧杂志,2024,60(3):73-78,6.基金项目
广东省重点领域研发计划(2022B0202110002) （2022B0202110002）
广东省"珠江人才计划"本土创新科研团队(2019BT02N630) （2019BT02N630）
广东省农业厅乡村振兴战略专项(粤农农计[2022]39号) （粤农农计[2022]39号）
