医学分子生物学杂志2024，Vol.21Issue(2)：166-170,5.DOI:10.3870/j.issn.1672-8009.2024.02.012
let-7i-5p在肿瘤中的研究进展
Research Progress on Role of let-7i-5p in Tumor
摘要
Abstract
let-7i-5p is a member of non-coding small molecule RNA(miRNA),which inhib-its tumor growth,proliferation and migration through multiple targets and signaling pathways.It also has the effect of regulating tumor microenvironment to delay cancer progression and improve tumor drug resistance.This article reviews the research progress of the mechanism of let-7i-5p in liver cancer,breast cancer,colon cancer,cervical cancer,nasopharyngeal cancer,kidney cancer and glioblastoma.It is expected to explore the role that let-7i-5p can play as a new tumor marker to pro-vide a new strategy for tumor prevention and treatment.关键词
let-7i-5p/肿瘤/机制研究Key words
let-7i-5p/tumor/mechanism分类
生物科学引用本文复制引用
偶勇,董佳琪,王斑,李媛媛,王树楷,晁旭..let-7i-5p在肿瘤中的研究进展[J].医学分子生物学杂志,2024,21(2):166-170,5.基金项目
国家自然科学基金(No.81774132),陕西省中医药"双链融合"中青年科研创新团队建设项目(No.2022-SLRH-LJ-010),陕西省中医药管理局科研项目(No.2021-zz-JC001) This work was supported by grants from the National Natural Science Foundation of China(No.81774132),Shaanxi Province Traditional Chinese Medicine"Double Chain Integration"Research and Innovation Team Building Project(No.2022-SLRH-LJ-010),Shaanxi Province Traditional Chinese Medicine Administration Research Project(No.2021-zz-JC001) （No.81774132）
