医学分子生物学杂志2024，Vol.21Issue(2)：171-175,5.DOI:10.3870/j.issn.1672-8009.2024.02.013
幽门螺杆菌毒力因子CagA的基因表达调控机制研究进展
Advances in Gene Expression Regulatory Mechanism of Helicobacter pylori Virluence Factor CagA
摘要
Abstract
About half of the global population has been found to be infected with Helicobacter pylori(H.pylori),with particularly high rates in developing countries.Currently,H.pylori infec-tion has been listed as a high-risk factor for the development of gastric cancer.The pathogenesis of H.pylori infection is believed to be associated with complex interactions between environment fac-tors,host susceptibilities,and bacterial pathogenicity.Therefore,this article reviews the molecular mechanism of the regulation of Helicobacter pylori independent factor cagA expression,in order to better understand the pathogenicity of cagA and to provide a theoretical reference for the future pre-vention and treatment of diseases caused by H.pylori.关键词
幽门螺杆菌/cagA/调控机制Key words
Helicobacter pylori/cytotoxin-associated gene A/regulatory mechanism分类
医药卫生引用本文复制引用
王萌萌,余梦超,王莉莉,赵振宇,董全江..幽门螺杆菌毒力因子CagA的基因表达调控机制研究进展[J].医学分子生物学杂志,2024,21(2):171-175,5.基金项目
国家自然科学基金(No.31870777) This work was supported by a grand from the National Natural Science Foundation of China(No.31870777) （No.31870777）
