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慢性HBV感染与代谢相关脂肪性肝病:已知与未知

耿楠 倪文婧 芮法娟 李婕

临床肝胆病杂志2024,Vol.40Issue(3):441-445,5.
临床肝胆病杂志2024,Vol.40Issue(3):441-445,5.DOI:10.12449/JCH240301

慢性HBV感染与代谢相关脂肪性肝病:已知与未知

Chronic hepatitis B virus infection and metabolic associated fatty liver disease:The known and unknown aspects

耿楠 1倪文婧 2芮法娟 2李婕3

作者信息

  • 1. 南京大学医学院附属鼓楼医院感染性疾病科,南京 210008
  • 2. 南京中医药大学鼓楼临床医学院感染性疾病科,南京 210008
  • 3. 南京大学医学院附属鼓楼医院感染性疾病科,南京 210008||南京中医药大学鼓楼临床医学院感染性疾病科,南京 210008
  • 折叠

摘要

Abstract

Chronic hepatitis B virus(HBV)infection is the main cause of the disease burden of viral hepatitis worldwide,and meanwhile,due to changes in lifestyle and dietary habits,the incidence rate of metabolic associated fatty liver disease(MAFLD)is constantly increasing,making MAFLD the leading chronic liver disease around the world.Chronic HBV infection comorbid with MAFLD is becoming more and more common in clinical practice.Metabolic factors,rather than viral factors,are the main cause of chronic HBV infection comorbid with MAFLD.During disease progression,steatohepatitis and fibrosis,rather than steatosis,are the main influencing factors for the progression to liver cirrhosis and hepatocellular carcinoma.For patients with chronic HBV infection and MAFLD,integrated management of virus and metabolic factors is of great importance.This article reviews the tissues regarding the interaction,prognosis,and clinical management of chronic HBV infection and MAFLD.

关键词

乙型肝炎病毒/乙型肝炎,慢性/代谢相关脂肪性肝病/预后/临床管理

Key words

Hepatitis B Virus/Hepatitis B,Chronic/Metabolic Dysfunction Associated Fatty Liver Disease/Prognosis/Clinical Management

引用本文复制引用

耿楠,倪文婧,芮法娟,李婕..慢性HBV感染与代谢相关脂肪性肝病:已知与未知[J].临床肝胆病杂志,2024,40(3):441-445,5.

基金项目

国家自然科学基金面上项目(819705457,82170609) (819705457,82170609)

江苏省自然科学基金面上项目(BK20231118) General Project of National Natural Science Foundation of China(819705457,82170609) (BK20231118)

General Project of National Science Foundation of Jiangsu Province(BK20231118) (BK20231118)

临床肝胆病杂志

OACSTPCD

1001-5256

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