临床肝胆病杂志2024,Vol.40Issue(3):473-477,5.DOI:10.12449/JCH240306
早期胰腺癌分子诊断专家共识(2023年版)
Expert consensus on the molecular diagnosis of early-stage pancreatic cancer(2023 edition)
摘要
Abstract
Pancreatic cancer is a relatively common tumor of the digestive system,with difficulties in early-stage diagnosis and an extremely high degree of malignancy.Molecular diagnostic technology based on tumor biomarkers,combined with the existing gold standard in clinical practice,is of great clinical significance to achieve early accurate identification,timely treatment and intervention,and reduction in mortality.Previous studies have shown that miRNAs show high specificity in terms of types and expression levels in different pathological stages of pancreatic cancer and can thus be used in monitoring the development and progression of pancreatic cancer.Since a single miRNA has a limited diagnostic potential,the combination of different miRNAs may effectively improve the diagnostic efficiency of early-stage pancreas carcinogenesis.Based on related research advances in recent years,this consensus document aims to fill the gap in molecular diagnostic technology in the guidelines for the clinical diagnosis and treatment of pancreatic cancer and provide expert guidance and recommendations.关键词
胰腺肿瘤/癌症早期检测/生物标记,肿瘤/微RNAs/专家共识Key words
Pancreatic Neoplasms/Early Detection of Cancer/Biomarkers,Tumor/MicroRNAs/Expert Consensus引用本文复制引用
中国医师协会临床精准医疗专业委员会,中国抗癌协会肿瘤胰腺病学专业委员会,肖桂山,郭俊超,郭晓钟..早期胰腺癌分子诊断专家共识(2023年版)[J].临床肝胆病杂志,2024,40(3):473-477,5.基金项目
国家自然科学基金(81770846,81642006) (81770846,81642006)
Hirshberg胰腺癌研究基金(AH201901083) (AH201901083)
康德生物癌症研究基金(KD2021030001) Natural National Science Foundation of China(81770846,81642006) (KD2021030001)
U.S.Hirshberg Foundation for Pancreatic Cancer Research(AH201901083) (AH201901083)
Kante Seeds Grant Foundation for Cancer Research(KD2021030001) (KD2021030001)