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磁共振质子密度脂肪分数(MRI-PDFF)在肝脂肪定量中的应用

杨晨 余上海 徐飞鹏 张华

临床肝胆病杂志2024,Vol.40Issue(3):600-605,6.
临床肝胆病杂志2024,Vol.40Issue(3):600-605,6.DOI:10.12449/JCH240327

磁共振质子密度脂肪分数(MRI-PDFF)在肝脂肪定量中的应用

Application of magnetic resonance imaging-proton density fat fraction in liver fat quantification

杨晨 1余上海 1徐飞鹏 1张华2

作者信息

  • 1. 上海中医药大学附属曙光医院肝硬化科,上海中医药大学肝病研究所,上海 201203
  • 2. 上海中医药大学附属曙光医院肝硬化科,上海中医药大学肝病研究所,上海 201203||肝肾疾病病证教育部重点实验室,上海 201203
  • 折叠

摘要

Abstract

Hepatic steatosis can be observed in chronic liver diseases of different etiologies.The main predisposing factors for hepatic steatosis include chronic viral hepatitis,cholestatic liver disease,alcoholic liver disease,and nonalcoholic fatty liver disease.Simple fatty liver disease is the initial manifestation of hepatic steatosis,followed by steatohepatitis,liver fibrosis,liver cirrhosis,and even hepatocellular carcinoma.With the development of medical imaging technology,magnetic resonance imaging-proton density fat fraction(MRI-PDFF)has been widely used in the diagnosis of fatty liver disease(FLD)in clinical practice.MRI-PDFF is gradually becoming the gold standard for the noninvasive diagnosis of FLD due to its high accuracy and good repeatability.This article reviews the clinical application of MRI-PDFF in liver fat quantification and related research advances.

关键词

脂肪肝/磁共振成像/质子密度脂肪分数/诊断

Key words

Fatty Liver/Magnetic Resonance Imaging/Proton Density Fat Fraction/Diagnosis

引用本文复制引用

杨晨,余上海,徐飞鹏,张华..磁共振质子密度脂肪分数(MRI-PDFF)在肝脂肪定量中的应用[J].临床肝胆病杂志,2024,40(3):600-605,6.

基金项目

2019年度上海市科学技术委员会"科技创新行动计划"临床医学领域科技支撑项目(19401972700) Shanghai Municipal Science and Technology Commission 2019"Science and Technology Innovation Action Plan"(Clinical Medicine)(19401972700) (19401972700)

临床肝胆病杂志

OA北大核心CSTPCD

1001-5256

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