临床肝胆病杂志2024，Vol.40Issue(3)：639-643,5.DOI:10.12449/JCH240334
中性粒细胞胞外诱捕网(NET)与肝脏疾病的关系
Research advances in neutrophil extracellular traps and liver diseases
摘要
Abstract
Neutrophils play an immune defense role by releasing the proteases such as neutrophil elastase and myeloperoxidase to form neutrophil extracellular trap(NET)and participate in the inflammatory response of various liver diseases,but the excessive release of NET may worsen liver tissue damage and has thus become one of the risk factors for liver diseases.In recent years,studies have shown that the excessive release of NET can promote the progression of liver diseases(such as viral hepatitis,nonalcoholic steatohepatitis,and hepatic ischemia-reperfusion injury)to liver cancer,and clarifying the mechanism of action of NET is of great importance for the diagnosis and progression of liver diseases.Therefore,this article elaborates on the latest research advances in NET in liver diseases,so as to provide new insights into the diagnosis and treatment of liver diseases and the prevention of liver cancer.关键词
胞外诱捕网/肝疾病/肝肿瘤Key words
Extracellular Traps/Liver Diseases/Liver Neoplasms引用本文复制引用
仁增卓嘎,杨康洁,芦永良,王志鑫,王海久..中性粒细胞胞外诱捕网(NET)与肝脏疾病的关系[J].临床肝胆病杂志,2024,40(3):639-643,5.基金项目
青海省科技厅临床医学研究中心项目(2017-SF-L2) Qinghai Provincial Department of Science and Technology Clinical Medical Research Center Project(2017-SF-L2) （2017-SF-L2）
