中风与神经疾病杂志2024，Vol.41Issue(3)：264-269,6.DOI:10.19845/j.cnki.zfysjjbzz.2024.0052
自身免疫性脑炎诊断要素的关联性与权重探讨
The inter-relationship and weight of diagnostic elements of autoimmune encephalitis
吴钢 1王成华 2黄宁俊 2廖建胜 2郑巧娟 2卢娅琴 2高晓菁 2陈明莲2
作者信息
- 1. 福建三博福能脑科医院神经内科,福建 福州 350025||福建医科大学附属第一医院神经内科(原单位),福建 福州 350004
- 2. 福建三博福能脑科医院神经内科,福建 福州 350025
- 折叠
摘要
Abstract
Objective To analyze the weights of limbic system symptoms,epilepsy,inflammatory cerebrospinal fluid(CSF),brain MRI-FLAIR findings,and video electroencephalogram(VEEG)findings in diagnosing autoimmune en-cephalitis(AE).Methods We calculated the mean weight rates(%)of limbic system symptoms,epilepsy,inflamma-tory CSF,brain MRI-FLAIR findings,and VEEG findings of 15 cases of AE admitted to our hospital from January to July 2023.Results The frequencies of the elements were as following:limbic system symptoms,14/15 cases;epilepsy,7/15 cases;inflammatory CSF,6/13 cases(all the 6 positive cases had increased lymphocyte and monocyte counts and/or in-creased microprotein levels;5 cases had normal white blood cell counts,but with increases in lymphocytes and monocytes indicated by CSF cytology analysis;and 2 cases were not examined);MRI-FLAIR abnormalities,13/15 cases;and VEEG abnormalities,12/15 cases.All the patients with seizures had both limbic system symptoms and abnormal MRI-FLAIR sig-nals in the limbic system,and abnormal brain regions on MRI-FLAIR all showed abnormal discharges on VEEG.The mean weight rates of limbic system symptoms,brain MRI-FLAIR abnormalities,and VEEG abnormalities were the high-est,which were 94.2%,96.4%and 79.9%,respectively.Conclusion Limbic system symptoms,abnormal VEEG abnor-malities,and MRI-FLAIR abnormalities are most frequent in AE.Cytology analysis is necessary for inflammatory CSF ex-amination.Seizures with limbic system symptoms are highly indicative of limbic encephalitis.关键词
自身免疫性脑炎/边缘系统/MRI-FLAIR/脑脊液/视频脑电图/诊断/权重Key words
Autoimmune encephalitis/Limbic system/MRI-FLAIR/Cerebrospinal fluid/Video electro-encephalogram/Dagnosis/Weight分类
医药卫生引用本文复制引用
吴钢,王成华,黄宁俊,廖建胜,郑巧娟,卢娅琴,高晓菁,陈明莲..自身免疫性脑炎诊断要素的关联性与权重探讨[J].中风与神经疾病杂志,2024,41(3):264-269,6.
