三维斑点追踪成像技术评估心房功能性二尖瓣反流患者左心室功能OA北大核心CSTPCD
Evaluation of left ventricular function in atrial functional mitral regurgitation patients by three-dimensional speckle tracking imaging
目的:应用三维斑点追踪成像技术(3D-STI)探讨心房功能性二尖瓣反流(AFMR)患者的左心室功能,并探讨其临床应用价值.方法:选取 82 例心房颤动患者,根据其有无AFMR分为单纯房颤组 48 例和心房AFMR组 34 例,另选取同时期40 例健康志愿者作为对照组.应用 3D-STI获取心肌整体纵向应变(GLS)、整体圆周应变(GCS)、整体径向应变(GRS)和左心室整体扭转角度峰值(LVPtw),比较上述参数在各组之间的差异.绘制 3D-STI各参数评价AFMR隐匿性左心室功能受损的ROC曲线,确定GLS、GCS、GRS及LVPtw对AFMR患者左心室功能受损的诊断效能.结果:与对照组相比,单纯房颤组GLS、GCS、GRS均降低,差异均具有统计学意义(P均<0.05);与对照组、单纯房颤组比较,AFMR组GLS、GCS、GRS、LVPtw均降低,差异均具有统计学意义(P均<0.05).ROC曲线分析显示,GLS、GCS、GRS和LVPtw诊断AFMR患者左心室功能受损的曲线下面积分别为 0.884、0.788、0.865 及 0.850.结论:应用 3D-STI可检测AFMR患者早期左心室心肌受损的情况,根据其心肌应变及心肌扭转参数,对指导临床进行早期干预具有一定的价值.
Objective:To utilize three-dimensional speckle tracking imaging(3D-STI)to assess left ventricular function in patients with atrial functional mitral regurgitation(AFMR)and explore its clinical application value.Methods:According to the presence or absence of mitral regurgitation,82 patients with atrial fibrillation were divided into simple atrial fibrillation group(n=48)and AFMR group(n=34).Additionally,40 healthy volunteers were selected as the control group.Global longitudinal strain(GLS),global circumferential strain(GCS),global radial strain(GRS)and left ventricular peak twist(LVPtw)were obtained by 3D-STI.The differences in the above parameters among the groups were compared.The receiver operating characteristic(ROC)curves were drawn to analyze the diagnostic efficacy of GLS,GCS,GRS and LVPtw in patients with left ventricular dysfunction in AFMR.Results:Compared with the control group,GLS,GCS and GRS in the simple atrial fibrillation group were significantly lower(all P<0.05),and GLS,GCS,GRS and LVPtw in the AFMR group were significantly lower than those in the control group and the simple atrial fibrillation group(all P<0.05).ROC curves showed that the areas under the curves of GLS,GCS,GRS and LVPtw in diagnosing left ventricular dysfunction in patients with AFMR were 0.884,0.788,0.865 and 0.850,respectively.Conclusion:The application of 3D-STI can detect early left ventricular myocardial damage in AFMR pa-tients,and based on their myocardial strain and torsion parameters,it has certain clinical significance for guiding clinical ear-ly intervention.
聂淑婷;周畅;孙恒;许涛;李安妮;董雅馨;胡文姝;李心怡
三峡大学第一临床医学院 宜昌市中心人民医院超声科,湖北 宜昌 443000
临床医学
二尖瓣闭锁不全心室功能,左超声心动描记术
Mitral Valve InsufficiencyVentricular Function,LeftEchocardiography
《中国临床医学影像杂志》 2024 (003)
174-177,196 / 5
湖北省宜昌市医疗卫生研究项目(No.A16-301-12).
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