中国临床医学影像杂志2024，Vol.35Issue(3)：178-181,4.DOI:10.12117/jccmi.2024.03.006
左右心功能相关参数及心室内径比值评估高原性肺动脉高压心功能损伤的价值分析
Value analysis of left and right ventricular function-related parameters and ventricular inner diameter ratio in evaluating cardiac function impairment in patients with high altitude pulmonary hypertension
摘要
Abstract
Objective:To investigate the value of left and right ventricular function parameters and the ratio of ventricular inner diameter in evaluating cardiac function impairment in patients with high altitude pulmonary hypertension(HPAH).Meth-ods:One hundred and eighteen patients with HPAH admitted to our hospital from April 2019 to April 2022 were enrolled,and were classified into two groups according to the presence or absence of cardiac function impairment,positive group and negative group.All patients underwent speckle tracking imaging and cardiac Doppler color ultrasound.Then comparison was conducted on tricuspid annular plane systolic excursion(TAPSE)parameters(displacement of TAPSE at the free wall of right ventricular(TAPSEfw),at the midpoint(TAPSmid)and at the interventricular septum(TAPSEint)),left and right cardiac function parameters(left ventricular end-diastolic volume(LVEDV),left ventricular ejection fraction(LVEF),right ventricular ejection frac-tion(RVEF),right ventricular systolic pressure(RVSP)),and right ventricular to left ventricular transverse diameter ratio(RVRDd/LVTDd).Receiver operating characteristic(ROC)curve was plotted to evaluate the value of the diagnostic value of TAPSE combined with left and right ventricular function-related parameters and RVRDd/LVTDd for HPAH complicated with cardiac function impairment.Results:TAPSEfw,TAPSmid,TAPSEint,LVEDV,LVEF and RVEF were significantly lower,and RVRDd/LVTDd and RVSP were remarkably higner in the positive group compared to the negative group(all P<0.05).The AUC of TAPSEfw,TAPSmid,TAPSEint,LVEDV,LVEF,RVEF,RVSP,and RVRDd/LVTDd for the prediction of HPHA complicated with cardiac function impairment were 0.728,0.755,0.730,0.653,0.683,0.767,0.730,and 0.704,with the sensitivities of 77.0%,81.4%,79.2%,76.4%,72.2%,79.9%,78.3%and 63.7%,and the specificities were 69.9%,72.2%,77.1%,73.8%,79.8%,84.9%,80.5%and 81.0%,respectively.Analysis denoted that the AUC(0.858),sensitivity(87.2%)and specificity(92.2%)of the combined detection of the above parameters were higher than those of the separate detection(P<0.05).Conclusion:Left and right cardiac function parameters and RVRDd/LVTDd have high diagnostic value for HPAH combined with cardiac func-tion impairment,and the combined AUC,sensitivity and specificity of each index are higher than those of each single test.关键词
肺动脉高压/心室功能/超声心动描记术Key words
Pulmonary Arterial Hypertension/Ventricular Function/Echocardiography分类
医药卫生引用本文复制引用
赵恩晨,金仁波,宁伟,蒲瑜,党国珍..左右心功能相关参数及心室内径比值评估高原性肺动脉高压心功能损伤的价值分析[J].中国临床医学影像杂志,2024,35(3):178-181,4.基金项目
青海省科技计划项目(2017-ZJ-754). （2017-ZJ-754）
