磁共振成像2024,Vol.15Issue(3):190-195,6.DOI:10.12015/issn.1674-8034.2024.03.031
昼夜节律在脑的多模态MRI中的研究进展
Research progress on circadian rhythms in multimodal MRI of the brain
摘要
Abstract
The presence of circadian rhythms causes diurnal fluctuations in brain structure and function.Currently,most neuroimaging studies do not control for the biological variable of time of day,making results less reproducible as well as complicating interpretation.In these years,the rapid development of multimodal MRI,voxel-based morphometry(VBM),diffusion magnetic resonance imaging(dMRI),functional magnetic resonance imaging(fMRI),magnetic resonance spectroscopy(MRS),and arterial spin labeling(ASL)methods have been used to study the influence of circadian rhythm on brain structure and function.Most studies have found significant effects of time of day on brain structure and function,but there are inconsistencies in the results reported.Current research has focused only on daytime time points and two or three-time points during the day,lacking research on nighttime time points and multiple time points during the day.We provide a review of recent progress in the study of circadian rhythms in MRI of the brain in order to increase awareness of time as a biological variable that influences neuroimaging studies.关键词
昼夜节律/脑结构/脑功能/多模态/磁共振成像Key words
circadian rhythm/brain structure/brain functional/multimodality/magnetic resonance imaging分类
医药卫生引用本文复制引用
邢寒棋,戴慧..昼夜节律在脑的多模态MRI中的研究进展[J].磁共振成像,2024,15(3):190-195,6.基金项目
National Natural Science Foundation of China(No.81971573). 国家自然科学基金项目(编号:81971573) (No.81971573)