基于16S rDNA测序对中重度牙周炎伴脑梗死患者龈下菌斑微生物群落结构分析OACSTPCD
Analysis of subgingival plaque microbiota community structure in moderate to severe periodontitis and cerebral infarction patients based on 16S rDNA sequencing
目的:运用16S rDNA测序比较分析中重度牙周炎伴脑梗死患者的龈下菌斑微生物群落结构特征及多样性,并初步探讨中重度牙周炎与脑梗死的相关性.方法:根据纳入和排除标准,采集中重度牙周炎患者10例(PD组)、中重度牙周炎伴脑梗死患者10例(CI-PD组)和健康人群10例(CK组)的龈下菌斑,通过Illumnia NovaSeq 6000测序平台对16S rDNA V3-V4区进行测序,运用Qiime、R、mothur及SPSS等软件进行生物信息学分析…查看全部>>
Objective:To compare the microbial community structure and diversity of subgingival plaque in patients with mod-erate to severe periodontitis and cerebral infarction by 16S rDNA sequencing,and to explore the relationship between moderate to severe periodontitis and cerebral infarction.Methods:According to the inclusion and exclusion criteria,subgingival plaque was col-lected from 10 patients with moderate to severe periodontitis(the PD group),10 patients wit…查看全部>>
钟晓雪;王慧;陈敏哲;常睿;贺小宁
海南医学院,海南 海口 570100海南医学院,海南 海口 570100海南医学院,海南 海口 570100海南医学院,海南 海口 570100海南医学院,海南 海口 570100||海南医学院第二附属医院口腔科,海南 海口 570100
口腔医学
16S rDNA微生物群落龈下菌斑牙周炎脑梗死
16S rDNAMicrobiota communitySubgingival microbiotaPeriodontitisCerebral infarction
《海南医学院学报》 2024 (6)
428-434,7
This study was supported by High-Level Talents Project of Hainan Natural Science Foundation(820RC768) 海南省自然科学基金高层次人才项目(820RC768)
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