郑州大学学报（医学版）2024，Vol.59Issue(2)：256-260,5.DOI:10.13705/j.issn.1671-6825.2023.09.020
非对比增强磁共振血管成像联合肾动态显像对动脉粥样硬化性肾动脉狭窄的诊断价值
Diagnostic value of non-contrast-enhanced magnetic resonance angiogra-phy combined with renal dynamic imaging in atherosclerotic renal artery stenosis
摘要
Abstract
Aim:To explore the diagnostic value of non-contrast enhanced magnetic resonance angiography(NCE-MRA)combined with renal dynamic imaging in atherosclerotic renal artery stenosis(ARAS).Methods:A total of 172 pa-tients who underwent renal artery digital subtraction angiography(DSA)in Henan University People's Hospital(Henan Pro-vincial People's Hospital)from January 2019 to January 2023 were selected and allocated into ARAS group(n =107)and non-ARAS group(n =65).Clinical characteristics of the2 groups and the diagnostic value of NCE-MRA for ARAS were an-alyzed.ROC curve was drawn with the ratio and difference of bilateral GFR measured by renal dynamic imaging and the combination of them and NCE-MRA diagnostic results to evaluate their diagnostic value for ARAS.Results:NCE-MRA and DSA were in good agreement in diagnosing ARAS(Kappa =0.828,P<0.01).The sensitivity,specificity,accuracy,positive predictive value(PPV)and negative predictive value(NPV)of NCE-MRA for diagnosing ARAS were 92.52%,90.77%,91.86%,94.29%,and 88.06%,respectively;the area under the ROC curve of the ratio and difference of bilateral GFR for diagnosing ARAS were 0.771 and 0.708,and the optimal diagnostic margins were 1.371 and 13.900 mL/(min·1.73 m2),the sensitive was 52.3%and 45.8%,and the specificity was 90.8%and 89.2%.The area under the ROC curve of the ratio and difference of bilateral GFR combined with NCE-MRA for diagnosing ARAS was 0.948 and 0.942,respective-ly,the sensitivity was 95.3%,94.4%,the specificity was 89.2%.Conclusion:NCE-MRA has high diagnostic efficiency for ARAS.Combination with GFR measured by renal dynamic imaging can improve the diagnostic efficiency of NCE-MRA for ARAS.关键词
非对比增强磁共振血管成像/肾动态显像/肾小球滤过率/动脉粥样硬化性肾动脉狭窄/诊断价值Key words
non-contrast enhanced magnetic resonance angiography/renal dynamic imaging/glomerular filtration rate/atherosclerotic renal artery stenosis/diagnostic value分类
医药卫生引用本文复制引用
刘敏,郝义彬,张晨,田丹丹,屈慧云,郭林雅,杜慧宇,黄琦,刘芷兰,王伊菲..非对比增强磁共振血管成像联合肾动态显像对动脉粥样硬化性肾动脉狭窄的诊断价值[J].郑州大学学报（医学版）,2024,59(2):256-260,5.基金项目
国家自然科学基金面上项目(82270463) （82270463）
河南省医学科技攻关项目(LHGJ20210025,LHGJ20220002) （LHGJ20210025,LHGJ20220002）
河南省重点研发专项(231111313400) （231111313400）
