郑州大学学报（医学版）2024，Vol.59Issue(2)：191-195,5.DOI:10.13705/j.issn.1671-6825.2023.09.012
多模态成像技术引导下组织间徒手插植近距离放射治疗宫颈癌的效果及剂量学分析
Application and dosimetric analysis of brachytherapy with free hand im-plantation for cervical cancer guided by multimodal imaging technology
摘要
Abstract
Aim:To explore the application and dosimetry of brachytherapy for cervical cancer with free hand implanta-tion guided by multimodal imaging technology.Methods:A total of 98 patients with cervical cancer were selected,and were allocated into study group(49 cases)and control group(49 cases).The control group was treated with CT image guided brachytherapy with intertissue free hand implantation.The study group conducted real-time ultrasound combined with CT im-age guided brachytherapy with intertissue free hand implantation.The implantation characteristics,efficacy,90%high risk clinical target volume dose(HR-CTVD90),cumulative doses of organ at risk and complications between the 2 groups were compared.Results:The time of single needle insertion in the study group was shorter than that in the control group(P<0.001).The efficacy of the study group at 3 and 6 months after brachytherapy was better than that of the control group(P<0.05).Tumor size of 5 to<6 cm HR-CTVD90 and6 to<7 cm HR-CTVD90 in the study group were higher than those in the control group(P<0.05).Bladder,sigmoid and rectal cumulative doses in the study group were lower than those in the control group(P<0.05).The total complication rate of the study group was lower than that of the control group(P = 0.036).Conclusion:Brachytherapy guided by multimodal imaging technology has good clinical efficacy,could effectively reduce the time of single needle insertion and the risk of complications and has dosimetry advantages.关键词
多模态成像技术/宫颈癌/徒手插植/近距离放射治疗/剂量学Key words
multimodal imaging technology/cervical cancer/free hand implantation/brachytherapy/dosimetry分类
医药卫生引用本文复制引用
于晓,成慧君,田淑贞,肖艳,杨柳..多模态成像技术引导下组织间徒手插植近距离放射治疗宫颈癌的效果及剂量学分析[J].郑州大学学报（医学版）,2024,59(2):191-195,5.基金项目
河南省医学科技攻关计划项目(LHGJ20210205) （LHGJ20210205）
