郑州大学学报（医学版）2024，Vol.59Issue(2)：227-231,5.DOI:10.13705/j.issn.1671-6825.2023.12.017
生态系统理论指导下的营养管理对急性淋巴细胞白血病化疗患儿营养状态的影响
Effects of nutrition management under the guidance of ecosystem theory on nutritional status of children undergoing chemotherapy for acute lym-phoblastic leukemia
摘要
Abstract
Aim:To analyze the effects of nutrition management under the guidance of ecosystem theory on nutritional status of children undergoing chemotherapy for acute lymphoblastic leukemia(ALL).Methods:A total of 86 children with ALL admitted to the hospital between January and December 2021 were enrolled,and were allocated into control group and observation group using group randomization method,with 43 in each group.Control group was given routine nutritional man-agement,while observation group was given nutrition management under the guidance of ecosystem theory.Before and after intervention,the serum levels of albumin(ALB),prealbumin(PA)and transferrin(TFN)were determined using full-auto-matic biochemical analyzer,upper arm circumference and skinfold thickness of deltoid were measured,cancer-related fatigue(CRF)degree was evaluated by Piper fatigue scale.The drug side effects during chemotherapy were recorded.Results:The degree of drop in serum levels of ALB,PA,TFN and upper arm circumference after intervention of observation group was less than that of control group(P<0.05),and the degree of drop in physical fatigue score,cognitive fatigue score,emotional fatigue score,and comprehensive fatigue score in observation group was more than that of control group(P<0.05).The to-tal incidence of granulopenia,thrombocytopenia,liver injury,nausea and vomiting,diarrhea and mucosal inflammation in ob-servation group was lower than that of control group(P<0.05).Conclusion:Nutrition management under the guidance of ecosystem theory can effectively maintain nutritional status,and improve chemotherapy tolerance of ALL children.关键词
急性淋巴细胞白血病/生态系统理论/营养管理Key words
acute lymphoblastic leukemia/ecosystem theory/nutrition management分类
医药卫生引用本文复制引用
向明丽,麻彦,李艺,易岚..生态系统理论指导下的营养管理对急性淋巴细胞白血病化疗患儿营养状态的影响[J].郑州大学学报（医学版）,2024,59(2):227-231,5.基金项目
河南省医学科技攻关计划项目(SBGJ202102106) （SBGJ202102106）
