郑州大学学报（医学版）2024，Vol.59Issue(2)：232-235,4.DOI:10.13705/j.issn.1671-6825.2023.03.076
异基因造血干细胞移植后合并巨细胞病毒肺炎的临床分析
Clinical analysis of cytomegalovirus pneumonia after allogeneic hemato-poietic stem cell transplantation
摘要
Abstract
Aim:To analyze the clinical characteristics of cytomegalovirus(CMV)pneumonia after allogeneic hemato-poietic stem cell transplantation(allo-HSCT).Methods:Clinical features and laboratory data of 29 patients with CMV pneu-monia after allo-HSCT from January 1,2019 to October 31,2022 at the First Affiliated Hospital of Zhengzhou University were collected.Results:Among the 29 patients,1 case with confirmed diagnosis,16 cases with clinical diagnosis,and 12 ca-ses with suspected diagnosis;18(62.1%)were effective and 11(37.9%)were ineffective after treatment.The proportion of the patients with other pathogenic microorganism infection(P =0.001),graft-versus-host disease(P =0.005),and invasive ventilation(P =0.018)in ineffective group were higher than those in effective group.Conclusion:It's difficult to diagnose definitely and treat CMV pneumonia after allo-HSCT.It's necessary to clarify the diagnosis as soon as possible,so to receive effective treatment earlier.关键词
巨细胞病毒肺炎/造血干细胞移植/异基因Key words
cytomegalovirus pneumonia/hematopoietic stem cell transplantation/allogeneic分类
医药卫生引用本文复制引用
张素平,边志磊,李丽,曹伟杰,秦菁,彭英楠,高思雨,万鼎铭..异基因造血干细胞移植后合并巨细胞病毒肺炎的临床分析[J].郑州大学学报（医学版）,2024,59(2):232-235,4.基金项目
国家自然科学基金项目(32100698) （32100698）
