昆明医科大学学报2024，Vol.45Issue(3)：59-64,6.DOI:10.12259/j.issn.2095-610X.S20240309
头颈4D-CTA结合SDF-1a/CXCR4信号通路评估颅内后交通动脉瘤破裂风险的价值
Value of Head and Neck 4D-CTA Combined with SDF-1a/CXCR4 Signaling Pathway in Assessing the Risk of Ruptured Intracranial Posterior Communicating Aneurysms
摘要
Abstract
Objective To investigate the value of 4D-CTA combined with SDF-1a/CXCR4 signaling pathway in evaluating the risk of intracranial aneurysm rupture.Methods Fifty patients with unruptured intracranial posterior communicating aneurysms and 50 patients with ruptured intracranial posterior communicating aneurysms were divided into unruptured group 1 and ruptured group 1.All patients underwent 4D-CTA examination and serumSDF-1alevel was detected.Non-ruptured group 1 was followed up for 12 months(After conservative treatment),on this basis,patients with ruptured posterior communicating aneurysms were included in ruptured group 2,and patients with unruptured posterior communicating aneurysms were included in non-ruptured group 2.Results The AUC values of Wn,AR,L,SR,SDF-1a and their combinations in diagnosing ruptured intracranial posterior communicating aneurysms were all greater than 0.70.The AUC values of Wn,AR,L,SR,SDF-1a and their combinations in predicting ruptured intracranial posterior communicating aneurysms in ruptured group 2 were all greater than 0.70.Conclusion 4D-CTA combined with SDF-1acan effectively distinguish ruptured intracranial posterior communicating aneurysms and predict the risk of rupture.关键词
4D-CTA/基质细胞衍生因子-1/颅内后交通动脉瘤破裂Key words
4D-CTA/SDF-1a/Ruptured posterior intracranial communicating aneurysm分类
医药卫生引用本文复制引用
徐艺铭,钟剑锋,李斌,周欣颜,朱红丽,梁靖,廖承德..头颈4D-CTA结合SDF-1a/CXCR4信号通路评估颅内后交通动脉瘤破裂风险的价值[J].昆明医科大学学报,2024,45(3):59-64,6.基金项目
云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目(202401AY0700-358) （202401AY0700-358）
云南省教育厅科学研究基金资助项目(2024J0399) （2024J0399）
昆明市心血管影像技术中心(2023-SW(技术)-04) （2023-SW(技术）
昆明市"十百千"工程(2021-SW(后背)-09). （2021-SW(后背）
