摘要
Abstract
Objective:To explore the effect of initial high flow nasal cannula(HFNC)or non-invasive ventilation(NIV)on vital signs,blood gas analysis,and treatment failure rate in patients with acute exacerbation of chronic obstructive pulmo-nary disease(AECOPD).Methods:The data of 80 patients with AECOPD admitted to Youxian District People's Hospital of Mianyang City from January 2021 to December 2022 were analyzed retrospectively.The patients were divided into HFNC group(n=42)and NIV group(n=38)according to different treatment methods.The two groups were compared on heart rate(HR),respiratory rate(RR),mean arterial pressure(MAP),pH value,partial pressure of carbon dioxide(PaCO2),and partial pressure of oxygen(PaO2)before treatment and 3 d after treatment.The incidence rates of adverse reactions and treatment outcomes were analyzed statistically.Results:After 3 days of treatment,compared with the NIV group,the HFNC group had lower HR,RR,PaCO2,and higher pH and PaO2values(P<0.05).The incidence of facial pressure injuries and dry mouth and nose in HFNC group was lower than that in NIV group(P<0.05).Compared with the NIV group,the HFNC group had shorter total respiratory support time and lower treatment failure rate(P<0.05).Conclusion:Compared with NIV,HFNC can improve vital signs and blood gas indicators in patients with AECOPD more effectively.In addition,it can shorten the total duration of respiratory support,and reduce treatment failure rate.关键词
慢性阻塞性肺疾病/急性加重期/经鼻高流量氧疗/无创通气/生命体征/血气分析/治疗失败率Key words
Chronic obstructive pulmonary disease/Acute exacerbation/High flow nasal cannula/Non-invasive ventila-tion/Vital sign/Blood gas analysis/Treatment failure rate分类
医药卫生
