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The role of SLC12A family of cation-chloride cotransporters and drug discovery methodologies

Shiyao Zhang Peifeng Li Zhengqiu Li Zhen Wang Yun Wang Ke Ding Yan Wang Jinwei Zhang Nur Farah Meor Azlan Sunday Solomon Josiah Jing Zhou Xiaoxia Zhou Lingjun Jie Yanhui Zhang Cuilian Dai Dong Liang

药物分析学报(英文)2023,Vol.13Issue(12):1471-1495,25.
药物分析学报(英文)2023,Vol.13Issue(12):1471-1495,25.DOI:10.1016/j.jpha.2023.09.002

The role of SLC12A family of cation-chloride cotransporters and drug discovery methodologies

The role of SLC12A family of cation-chloride cotransporters and drug discovery methodologies

Shiyao Zhang 1Peifeng Li 2Zhengqiu Li 3Zhen Wang 4Yun Wang 5Ke Ding 4Yan Wang 1Jinwei Zhang 6Nur Farah Meor Azlan 7Sunday Solomon Josiah 7Jing Zhou 5Xiaoxia Zhou 1Lingjun Jie 1Yanhui Zhang 1Cuilian Dai 1Dong Liang8

作者信息

  • 1. Xiamen Cardiovascular Hospital of Xiamen University,School of Medicine,Xiamen University,Xiamen,Fujian,363001,China
  • 2. Institute for Translational Medicine,Qingdao University,Qingdao,Shandong,266021,China
  • 3. School of Pharmacy,Jinan University,Guangzhou,510632,China
  • 4. State Key Laboratory of Chemical Biology,Research Center of Chemical Kinomics,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai,200032,China
  • 5. Department of Neurology,Institutes of Brain Science,State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science,Institute of Biological Science,Zhongshan Hospital,Fudan University,Shanghai,200032,China
  • 6. Xiamen Cardiovascular Hospital of Xiamen University,School of Medicine,Xiamen University,Xiamen,Fujian,363001,China||Institute of Biomedical and Clinical Sciences,Medical School,Faculty of Health and Life Sciences,University of Exeter,Exeter,EX4 4PS,UK||State Key Laboratory of Chemical Biology,Research Center of Chemical Kinomics,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai,200032,China
  • 7. Institute of Biomedical and Clinical Sciences,Medical School,Faculty of Health and Life Sciences,University of Exeter,Exeter,EX4 4PS,UK
  • 8. Aurora Discovery Inc.,Foshan,Guangdong,528300,China
  • 折叠

摘要

关键词

Cation-chloride cotransporters/Chloride volume regulation/Cotransporter assays/Drug discovery

Key words

Cation-chloride cotransporters/Chloride volume regulation/Cotransporter assays/Drug discovery

引用本文复制引用

Shiyao Zhang,Peifeng Li,Zhengqiu Li,Zhen Wang,Yun Wang,Ke Ding,Yan Wang,Jinwei Zhang,Nur Farah Meor Azlan,Sunday Solomon Josiah,Jing Zhou,Xiaoxia Zhou,Lingjun Jie,Yanhui Zhang,Cuilian Dai,Dong Liang..The role of SLC12A family of cation-chloride cotransporters and drug discovery methodologies[J].药物分析学报(英文),2023,13(12):1471-1495,25.

基金项目

We are very grateful for the financial support from the National Natural Science Foundation of China(Grant Nos.:82170406,81970238,and 32111530119),Shanghai Municipal Science and Technology Major Project,China(Grant No.:2018SHZDZX01),The Royal Society UK(Grant No.:IEC\NSFC\201094),and the Commonwealth Scholarship Commission UK(Grant No.:NGCA-2020-43). (Grant Nos.:82170406,81970238,and 32111530119)

药物分析学报(英文)

OACSCD

2095-1779

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