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Gut dysbiosis aggravates cognitive deficits,amyloid pathology and lipid metabolism dysregulation in a transgenic mouse model of Alzheimer's disease

Chang Qu Qing-Qing Xu Wen Yang Mei Zhong Qiuju Yuan Yan-Fang Xian Zhi-Xiu Lin

药物分析学报（英文）2023，Vol.13Issue(12)：1526-1547,22.

药物分析学报（英文）2023，Vol.13Issue(12)：1526-1547,22.DOI:10.1016/j.jpha.2023.07.014

Gut dysbiosis aggravates cognitive deficits,amyloid pathology and lipid metabolism dysregulation in a transgenic mouse model of Alzheimer's disease

Chang Qu ¹Qing-Qing Xu ²Wen Yang ²Mei Zhong ²Qiuju Yuan ³Yan-Fang Xian ²Zhi-Xiu Lin⁴

作者信息

1. School of Chinese Medicine,Faculty of Medicine,The Chinese University of Hong Kong,Hong Kong,China||College of Forestry and Landscape Architecture,South China Agricultural University,Guangzhou,510640,China
2. School of Chinese Medicine,Faculty of Medicine,The Chinese University of Hong Kong,Hong Kong,China
3. Centre for Regenerative Medicine and Health,Hong Kong Institute of Science & Innovation,Chinese Academy of Sciences,Hong Kong Science Park,Shatin,N.T.,Hong Kong,China
4. School of Chinese Medicine,Faculty of Medicine,The Chinese University of Hong Kong,Hong Kong,China||Hong Kong Institute of Integrative Medicine,The Chinese University of Hong Kong,Hong Kong,China
折叠

摘要

关键词

Alzheimer's disease/Gut dysbiosis/Neuropathology/TgCRND8 mice

Key words

Alzheimer's disease/Gut dysbiosis/Neuropathology/TgCRND8 mice

引用本文复制引用

Chang Qu,Qing-Qing Xu,Wen Yang,Mei Zhong,Qiuju Yuan,Yan-Fang Xian,Zhi-Xiu Lin..Gut dysbiosis aggravates cognitive deficits,amyloid pathology and lipid metabolism dysregulation in a transgenic mouse model of Alzheimer's disease[J].药物分析学报（英文）,2023,13(12):1526-1547,22.

基金项目

This work was partially supported by National Natural Science Foundation of China(Project No.:82104414),Natural Science Foundation of Guangdong Province of China(Project No.:2022A1515011682)and a direct grant from The Chinese University of Hong Kong(Project No.:2021.071). （Project No.:82104414）

药物分析学报（英文）

OACSCD

ISSN：2095-1779

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