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Distinct molecular targets of ProEGCG from EGCG and superior inhibition of angiogenesis signaling pathways for treatment of endometriosis

Sze Wan Hung Yi Song Yao Wang Jacqueline Pui Wah Chung Tak Hang Chan Roman A.Zubarev Chi Chiu Wang Massimiliano Gaetani Yiran Li Zhouyurong Tan Xu Zheng Ruizhe Zhang Yang Ding Gene Chi Wai Man Tao Zhang

药物分析学报（英文）2024，Vol.14Issue(1)：100-114,15.

药物分析学报（英文）2024，Vol.14Issue(1)：100-114,15.DOI:10.1016/j.jpha.2023.09.005

Distinct molecular targets of ProEGCG from EGCG and superior inhibition of angiogenesis signaling pathways for treatment of endometriosis

Sze Wan Hung ¹Yi Song ¹Yao Wang ¹Jacqueline Pui Wah Chung ¹Tak Hang Chan ²Roman A.Zubarev ³Chi Chiu Wang ⁴Massimiliano Gaetani ⁵Yiran Li ¹Zhouyurong Tan ¹Xu Zheng ¹Ruizhe Zhang ⁶Yang Ding ¹Gene Chi Wai Man ¹Tao Zhang¹

作者信息

1. Department of Obstetrics & Gynaecology,The Chinese University of Hong Kong,Hong Kong,China
2. Department of Chemistry,McGill University,Montreal,H3A2K6,Canada
3. Division of Physiological Chemistry I,Department of Medical Biochemistry and Biophysics,Karolinska Institutet,Stockholm,SE 17177,Sweden||Unit of Chemical Proteomics,Science for Life Laboratory(SciLifeLab),Stockholm,SE 17177,Sweden||Department of Pharmacological & Technological Chemistry,I.M.Sechenov First Moscow State Medical University,Moscow,119146,Russia
4. Department of Obstetrics & Gynaecology,The Chinese University of Hong Kong,Hong Kong,China||Reproduction and Development,Li Ka Shing Institute of Health Sciences,The Chinese University of Hong Kong,Hong Kong,China||School of Biomedical Sciences,The Chinese University of Hong Kong,Hong Kong,China||Chinese University of Hong Kong-Sichuan University Joint Laboratory in Reproductive Medicine,The Chinese University of Hong Kong,Hong Kong,China
5. Division of Physiological Chemistry I,Department of Medical Biochemistry and Biophysics,Karolinska Institutet,Stockholm,SE 17177,Sweden||Chemical Proteomics Core Facility,Department of Medical Biochemistry and Biophysics,Karolinska Institutet,Stockholm,SE 17177,Sweden||Unit of Chemical Proteomics,Science for Life Laboratory(SciLifeLab),Stockholm,SE 17177,Sweden
6. Department of Obstetrics & Gynaecology,The Chinese University of Hong Kong,Hong Kong,China||Center for Reproductive Medicine,Henan Key Laboratory of Reproduction and Genetics,The First Affiliated Hospital of Zhengzhou University,Zhengzhou,450003,China
折叠

摘要

关键词

Molecular targets/ProEGCG/EGCG/Angiogenesis/Treatment/Endometriosis

Key words

Molecular targets/ProEGCG/EGCG/Angiogenesis/Treatment/Endometriosis

引用本文复制引用

Sze Wan Hung,Yi Song,Yao Wang,Jacqueline Pui Wah Chung,Tak Hang Chan,Roman A.Zubarev,Chi Chiu Wang,Massimiliano Gaetani,Yiran Li,Zhouyurong Tan,Xu Zheng,Ruizhe Zhang,Yang Ding,Gene Chi Wai Man,Tao Zhang..Distinct molecular targets of ProEGCG from EGCG and superior inhibition of angiogenesis signaling pathways for treatment of endometriosis[J].药物分析学报（英文）,2024,14(1):100-114,15.

基金项目

This work was supported by the GRF RGC & CRF,Hong Kong(Grant Nos.:475012 and C5045-20 EF) （Grant Nos.:475012 and C5045-20 EF）

HMRF,Hong Kong(Grant No.:03141386) （Grant No.:03141386）

ITF,Hong Kong(Grant No.:ITS/209/12) （Grant No.:ITS/209/12）

UGC Direct Grant 2011,2012,2021.032 （）

HKOG Trust Fund 2011,2014,2019 （）

and the National Natural Science Foundation of China(Grant Nos.:81974225 and 82201823).The Chemical proteomics core facility at Biomedicum(MBB,Karolinska Institute),also the Unit of SciLifeLab and part of the Swedish National Infrastructure for Biological Mass Spectrometry(BioMS),provided full support in the experimental design and the performance of the proteomics analysis using the Proteome Integral Solubility Alteration(PISA)assay for target dis-covery,with relative data analysis. （Grant Nos.:81974225 and 82201823）

药物分析学报（英文）

ISSN：2095-1779

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