中国骨伤2024，Vol.37Issue(3)：306-310,5.DOI:10.12200/j.issn.1003-0034.20221304
脂肪栓塞综合征的临床表现及影像诊断分析
Clinical manifestation and imaging diagnostic analysis of fat embolism syndrome
摘要
Abstract
Objective To explore characteristics of clinical and imaging findings in patients with fat embolism syndrome.Methods From January 2021 to October 2022,clinical manifestations of 13 patients with fat embolism due to fracture or or-thopaedic surgery were retrospectively analyzed,including 11 males and 2 females,aged from 17 to 60 years old.Mental and respiratory abnormalities and changes in vital signs occurred after admission or after surgery,and patient's chest and brain imaging results were abnormal.The patient's mental and respiratory abnormalities,vital signs,chest and brain imaging results were continuously monitored.Results The main clinical manifestations of fat embolism syndrome were abnormal pulmonary respiration in 13 patients,abnormal central nervous function in 7 patients,and spotted rash in 2 patients.Chest CT showed dif-fuse distribution of ground glass shadows in 13 patients,and severe symptoms were"snowstorm".Nine patients with ground glass fusion consolidation,5 patients with multiple nodules and 4 patients accompanied by bilateral pleural effusion.Head CT findings of 5 patients were negative,and head MRI findings of 1 patient showed multiple T1WI low signal,T2WI high signal shadow,DWI high signal shadow,and"starry sky sign"in basal ganglia,radiative crown,hemioval center,thalamus,frontal parietal cortex and subcortex.Conclusion Fat embolism syndrome has a high mortality rate.Clinical manifestations of respira-tory system and nervous system are not specific,and the skin spot rash has a characteristic manifestation.The"blizzard"sign is the specific manifestation of chest X-ray and CT examination of fat embolism,and the"starry sky"sign is the typical manifesta-tion of diffusion-weighted sequence of brain MRI examination of fat embolism.关键词
脂肪栓塞综合征/临床表现/影像学Key words
Fat embolism syndrome/Clinical manifestation/Imaging分类
医药卫生引用本文复制引用
但倩,吴海燕,黄昀桀,罗飞,李旭雪..脂肪栓塞综合征的临床表现及影像诊断分析[J].中国骨伤,2024,37(3):306-310,5.基金项目
四川省干部保健科科研课题项目(编号:川干研2021-608)Scientific Research Topic Project of Cadre Health Care Department in Sichuan Province(No.2021-608) （编号:川干研2021-608）
