中国体外循环杂志2024，Vol.22Issue(1)：8-12,5.DOI:10.13498/j.cnki.chin.j.ecc.2024.01.03
体外膜氧合辅助发生急性肾损伤的危险因素分析
Analysis of risk factors of acute kidney injury during extracorporeal membrane oxygenation assistance
摘要
Abstract
Objective To investigate the risk factors of acute kidney injury(AKI)in patients treated with extracorporeal membrane oxygenation(ECMO).Methods Methods A retrospective study was performed on 31 patients who received ECMO in Yueyang Central Hospital of Hunan Province from November 2015 to January 2024 to explore the risk factors of AKI.The basic conditions of patients before ECMO and the relevant clinical conditions during ECMO were collected,and the patients were divided into non-AKI group and AKI group according to whether they developed AKI.Univariate analysis and logistic regression analysis were used to identify potential risk factors that may affect AKI.Results Univariate analysis showed that 16 patients(51.6%)with AKI were associated with pre-ECMO hyperhematocrit,initial ECMO flow,large-scale myocardial infarction,and cumulative days of positive fluid equilibrium.The results of multivariate analysis showed that hematocrit(OR 1.24,95%CI:1.027～1.488;P = 0.025)and cumulative days of positive fluid equilibrium during ECMO treatment(OR 2.23,95%CI:1.126～4.418;P = 0.021)were risk factors for AKI in ECMO patients.Conclusion Hematocrit and cumulative days of positive fluid equilibrium during ECMO treatment and hematocrit are risk factors for AKI in patients undergoing ECMO.关键词
体外膜氧合/急性肾损伤/危险因素/液体管理Key words
Extracorporeal membrane oxygenation/Acute kidney injury/Risk factor/Fluid management引用本文复制引用
熊文芳,姚岚,王辉,韩钱鹏,蒋沁娟..体外膜氧合辅助发生急性肾损伤的危险因素分析[J].中国体外循环杂志,2024,22(1):8-12,5.基金项目
湖南省岳阳市科技局基础研究指导计划项目(岳市科发[2020]21号):吴阶平医学基金会临床科研专项资助基金(320.6750.2021-08-1) （岳市科发[2020]21号）
