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体外循环小鼠模型研究进展

董文豪 王添隆 吉冰洋

中国体外循环杂志2024,Vol.22Issue(1):50-54,5.
中国体外循环杂志2024,Vol.22Issue(1):50-54,5.DOI:10.13498/j.cnki.chin.j.ecc.2024.01.11

体外循环小鼠模型研究进展

Research advances on extracorporeal circulation in mice model

董文豪 1王添隆 2吉冰洋2

作者信息

  • 1. 100037 北京,中国医学科学院北京协和医学院,国家心血管病中心,阜外医院体外循环科||10003 北京,首都医科大学麻醉科
  • 2. 100037 北京,中国医学科学院北京协和医学院,国家心血管病中心,阜外医院体外循环科
  • 折叠

摘要

Abstract

Extracorporeal circulation(ECC)can artificially replace part or all cardiopulmonary function of patients.It plays a crucial role in cardiac surgery and life-saving support for patients with cardiopulmonary failure.Establishing a reliable animal model of ECC is essential to explore the mechanism of ECC on the body,and lead to the optimization of clinical management strategies.Recently,mice have been selected for establishing ECC models due to their advantages,including easy availability,diverse genotypes and high reproducibility.However,there is currently no standardized protocol of mice ECC model establishment.Therefore,it is necessary to conduct a literature review to provide theoretical foundations for establishing stable mice ECC model in the future.

关键词

体外循环/心肺转流/小鼠/模型建立

Key words

Extracorporeal circulation/Cardiopalmonary bypass/Mice/Model establishment

引用本文复制引用

董文豪,王添隆,吉冰洋..体外循环小鼠模型研究进展[J].中国体外循环杂志,2024,22(1):50-54,5.

基金项目

国家自然科学基金资助项目(82070479) (82070479)

中国体外循环杂志

OACSTPCD

1672-1403

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