中国内镜杂志2024，Vol.30Issue(3)：1-6,6.DOI:10.12235/E20230248
环周预切开内镜黏膜切除术治疗直径小于1cm的直肠神经内分泌肿瘤的有效性和安全性
The effectiveness and safety of endoscopic mucosal resection with precutting for rectal neuroendocrine neoplasm smaller than 1 cm in diameter
摘要
Abstract
Objective To investigate the effectiveness and safety of endoscopic mucosal resection with precutting(EMR-P)for the treatment of rectal neuroendocrine neoplasm(RNEN)smaller than 1 cm in diameter.Methods Clinical data of 177 patients with RNEN smaller than 1 cm in diameter from December 2016 to December 2021 were retrospectively analyzed.According to different treatment protocols,177 patients with RNEN were divided into endoscopic mucosal resection(EMR)group(n = 46),EMR-P group(n = 40)and endoscopic submucosal dissection(ESD)group(n = 91).The en bloc resection rate,complete resection rate,operation time,postoperative hospitalization time and incidence of operative complications among the three groups were compared.Results The complete resection rate in the EMR-P group(95.0%)and ESD group(97.8%)were significantly higher than that in the EMR group(87.0%)(P<0.05);The operation time in the EMR-P group(9.86±2.23)min was longer than that in the EMR group(4.12±0.88)min,EMR-P group and EMR group were shorter than that in the ESD group(19.55±3.67)min,the difference was statistically significant(P<0.05);Postoperative hospitalization time in the EMR group was(2.45±0.29)d and EMR-P group was(2.43±0.23)d,which were shorter than that in the ESD group(3.30±0.32)d,and the difference was statistically significant(P<0.05).There were no significant difference in the rates of en bloc resection and operative complications among the three groups(P>0.05).Conclusion EMR-P for the treatment of RNEN<1 cm in diameter has the advantages,such as simple operation,short operation time and hospitalization time,high histological complete resection rate and low complication rate,which is worthy of clinical application.关键词
直肠神经内分泌肿瘤(RNEN)/环周预切开内镜黏膜切除术(EMR-P)/内镜黏膜切除术(EMR)/内镜黏膜下剥离术(ESD)/治疗方法Key words
rectal neuroendocrine neoplasm(RNEN)/endoscopic mucosal resection with precutting(EMR-P)/endoscopic mucosal resection(EMR)/endoscopic submucosal dissection(ESD)/therapeutics分类
医药卫生引用本文复制引用
石磊,赵元顺,张浩,钱晶瑶,杨潇,李文,张姝翌..环周预切开内镜黏膜切除术治疗直径小于1cm的直肠神经内分泌肿瘤的有效性和安全性[J].中国内镜杂志,2024,30(3):1-6,6.基金项目
中华人民共和国科技部国家重点研发计划(No:2022YFC3602105) （No:2022YFC3602105）
