赣南医学院学报2024,Vol.44Issue(2):201-205,5.DOI:10.3969/j.issn.1001-5779.2024.02.019
慢性自发性荨麻疹与肠道菌群的关系
The advances of the relationship between chronic spontaneous urticarial and gut flora
王琨 1尤聪 2曾招林2
作者信息
- 1. 赣南医科大学第一临床医学院
- 2. 赣南医科大学第一附属医院皮肤性病科 国家皮肤与免疫性疾病临床研究中心分中心,江西 赣州 341000
- 折叠
摘要
Abstract
Chronic spontaneous urticaria(CSU)is a common chronic inflammatory disease in dermatology,but its pathogenesis is still inconclusive.The gut flora is the largest micro-ecological system in the human body,and it has a major impact on the regulation and development of the immune system.Recent studies have shown that there is a decrease in gut flora biodiversity and composition disorder in CSU patients.The main manifestation is the reduction of beneficial bacteria such as firmicutes and bacteroides,The increase of opportunistic pathogens such as proteus,the involvement of gut flora in the pathogenesis of CSU may be related to the role of its metabolic product short-chain fatty acids This article reviews the relationship between CSU and gut flora,summarizes the possible pathological mechanism and the composition changes of gut flora in CSU patients,trying to provides theoretical and literature reference for CSU treatment based on gut flora.关键词
慢性自发性荨麻疹/肠道菌群/幽门螺杆菌Key words
Chronic spontaneous urticaria/Gut flora/Helicobacter pylori分类
医药卫生引用本文复制引用
王琨,尤聪,曾招林..慢性自发性荨麻疹与肠道菌群的关系[J].赣南医学院学报,2024,44(2):201-205,5.