结核与肺部疾病杂志2024，Vol.5Issue(2)：172-178,7.DOI:10.19983/j.issn.2096-8493.20240040
长链非编码RNA在慢性阻塞性肺疾病中的表达及其作用研究进展
Progress in the expression of long-stranded noncoding RNA and their role in chronic obstructive pulmonary disease
摘要
Abstract
Chronic obstructive pulmonary disease(COPD)is a kind of preventable and treatable chronic lung disease characterized by persistent respiratory symptoms and airflow limitation.Long non-coding RNA(lncRNA)is a class of transcription products with long nucleotide chains that exert a variety of biological effects by regulating the expression of related molecules in various forms.In recent years,it has been demonstrated that lncRNA can be involved in the pathological response of COPD by regulating various molecular biological processes such as inflammatory response,oxidative stress and apoptosis,and have gradually become an important target for the diagnosis and treatment of COPD.In this paper,we reviewed the research progress of lncRNA expression in COPD,oxidative stress,human pulmonary microvascular endothelial cells apoptosis,and their role in pathological mechanisms,with the aim of providing new ideas and directions for the diagnosis and efficacy assessment of COPD.关键词
肺疾病,慢性阻塞性/RNA/病理过程/综述文献(主题)Key words
Pulmonary disease,chronic obstructive/RNA/Pathologic processes/Review literature as topic分类
医药卫生引用本文复制引用
闫彦峰,漆文霞,崔永慧,魏彩虹..长链非编码RNA在慢性阻塞性肺疾病中的表达及其作用研究进展[J].结核与肺部疾病杂志,2024,5(2):172-178,7.基金项目
Innovation Fund Project of the Fourth Affiliated Hospital of Gansu University of Traditional Chinese Medicine(GSBSHYY-2022-05,GSBSHYY-2021-01)兰州石化总医院(甘肃中医药大学第四附属医院)院内创新基金项目(GSBSHYY-2022-05,GSBSHYY-2021-01) （GSBSHYY-2022-05,GSBSHYY-2021-01）
