四川大学学报（医学版）2024，Vol.55Issue(2)：243-248,6.DOI:10.12182/20240360507
细菌纤维素复合材料在骨组织工程领域的应用新进展
New Advances in the Application of Bacterial Cellulose Composite Materials in the Field of Bone Tissue Engineering
摘要
Abstract
Bacterial cellulose(BC)is a type of extracellular polymeric nanomaterial secreted by microorganisms over the course of their growth.It has gained significant attention in the field of bone tissue engineering due to its unique structure of three-dimensional fibrous network,excellent biocompatibility,biodegradability,and exceptional mechanical properties.Nevertheless,BC still has some weaknesses,including low osteogenic activity,a lack of antimicrobial properties,small pore size,issues with the degradation rate,and a mismatch in bone tissue regeneration,limiting its standalone use in the field of bone tissue engineering.Therefore,the modification of BC and the preparation of BC composite materials have become a recent research focus.Herein,we summarized the relationships between the production,modification,and bone repair applications of BC.We introduced the methods for the preparation and the modification of BC.Additionally,we elaborated on the new advances in the application of BC composite materials in the field of bone tissue engineering.We also highlighted the existing challenges and future prospects of BC composite materials.关键词
细菌纤维素/生物基复合材料/骨组织工程/生物医用材料/综述Key words
Bacterial cellulose/Biobased composite materials/Bone tissue engineering/Biomedical materials/Review引用本文复制引用
罗川,张莉,冉力瑜,尤炫合,黄石书..细菌纤维素复合材料在骨组织工程领域的应用新进展[J].四川大学学报（医学版）,2024,55(2):243-248,6.基金项目
国家自然科学基金(No.81874027)资助 （No.81874027）
