四川大学学报（医学版）2024，Vol.55Issue(2)：469-474,6.DOI:10.12182/20240360505
成纤维细胞生长因子7在颅颌面发育中的作用
Role of Fibroblast Growth Factor 7 in Craniomaxillofacial Development
摘要
Abstract
Craniomaxillofacial development involves a series of highly ordered temporal-spatial cellular differentiation processes in which a variety of cell signaling factors,such as fibroblast growth factors,play important regulatory roles.As a classic fibroblast growth factor,fibroblast growth factor 7(FGF7)serves a wide range of regulatory functions.Previous studies have demonstrated that FGF7 regulates the proliferation and migration of epithelial cells,protects them,and promotes their repair.Furthermore,recent findings indicate that epithelial cells are not the only ones subjected to the broad and powerful regulatory capacity of FGF7.It has potential effects on skeletal system development as well.In addition,FGF7 plays an important role in the development of craniomaxillofacial organs,such as the palate,the eyes,and the teeth.Nonetheless,the role of FGF7 in oral craniomaxillofacial development needs to be further elucidated.In this paper,we summarized the published research on the role of FGF7 in oral craniomaxillofacial development to demonstrate the overall understanding of FGF7 and its potential functions in oral craniomaxillofacial development.关键词
成纤维细胞生长因子7/颅颌面发育/骨骼发育/综述Key words
Fibroblast growth factor 7/Craniomaxillofacial development/Skeletal development/Review引用本文复制引用
王蕊欣,安可,谢静,邹淑娟..成纤维细胞生长因子7在颅颌面发育中的作用[J].四川大学学报（医学版）,2024,55(2):469-474,6.基金项目
国家自然科学基金(No.82071150)资助 （No.82071150）
