军事医学2024，Vol.48Issue(2)：95-100,6.DOI:10.7644/j.issn.1674-9960.2024.02.003
2.6GHz射频暴露条件下离体神经元网络的剂量学研究
Dosimetric study of isolated neuronal networks under 2.6 GHz radiofrequency exposure
汪雨晴 1赵雪龙 2刘琦 2董国福 2隗雨 3陈妮 4刘小曼 2王长振 2周红梅1
作者信息
- 1. 安徽医科大学基础医学院,合肥 230032||军事科学院军事医学研究院辐射医学研究所,北京 100850
- 2. 军事科学院军事医学研究院辐射医学研究所,北京 100850
- 3. 军事科学院军事医学研究院辐射医学研究所,北京 100850||河北大学生命科学学院,河北保定 071000
- 4. 安徽医科大学基础医学院,合肥 230032
- 折叠
摘要
Abstract
Objective To evaluate the characteristics of dose distribution of neuronal networks in vitro on microelectrode arrays(MEAs)under 2.6 GHz radiofrequency(RF)exposure.Methods The MEAs were coupled with a real-time RF exposure setup,and electromagnetic simulation software was used to calculate the RF dose absorbed in cultured neuronal networks.A fiber-optic temperature probe was used for experimental validation and monitoring of the cell temperature during RF exposure.The MEAs were used to record the electrical activity of neurons.Results For an input power of 1 W,a specific absorption rate(SAR)level of(15.51±2.48)W/kg was calculated,and the variability of the SAR distribution was 16%.In our experimental system,the temperature elevation of neurons was up to 0.15℃for an SAR of 4 W/kg RF exposure.Conclusion The exposure device can provide high SAR efficiency and uniformity in the 2.6 GHz band,which is suitable for studying the real-time effects of RF fields on the electrical activity of neuronal networks in the 5G network band.关键词
微电极阵列/射频场/神经元网络/剂量学/5G网络Key words
microelectrode array/radiofrequency fields/neuronal networks/dosimetry/5G network分类
医药卫生引用本文复制引用
汪雨晴,赵雪龙,刘琦,董国福,隗雨,陈妮,刘小曼,王长振,周红梅..2.6GHz射频暴露条件下离体神经元网络的剂量学研究[J].军事医学,2024,48(2):95-100,6.
